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口服蓝色染料引起的急性泛发性发疹性脓疱病。

Acute generalized exanthematous pustulosis due to oral use of blue dyes.

机构信息

Division of Allergy, Department of Internal Medicine, Gülhane Military Medical Academy and Medical School, Ankara, Turkey.

出版信息

Korean J Intern Med. 2011 Sep;26(3):360-3. doi: 10.3904/kjim.2011.26.3.360. Epub 2011 Sep 13.

DOI:10.3904/kjim.2011.26.3.360
PMID:22016599
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3192211/
Abstract

Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents are most frequently antibacterial drugs. We present a patient with acute generalized exanthematous pustulosis caused by methylene blue and indigotin dyes.

摘要

急性泛发性发疹性脓疱病是一种罕见的严重脓疱性皮肤不良反应，其特征为具有典型组织学表现的快速临床病程。它伴有发热和弥漫性红斑上非毛囊性脓疱的急性发疹。最常见的致病药物为抗菌药物。我们报告了一例由亚甲蓝和靛蓝染料引起的急性泛发性发疹性脓疱病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/3192211/771f435a96cf/kjim-26-360-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/3192211/1c7020254dc7/kjim-26-360-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/3192211/771f435a96cf/kjim-26-360-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/3192211/1c7020254dc7/kjim-26-360-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3f5/3192211/771f435a96cf/kjim-26-360-g002.jpg

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[Immediate patent blue-induced hypersensitivity during sentinel node detection: The value of cutaneous tests].[前哨淋巴结检测期间即刻专利蓝诱导的超敏反应：皮肤试验的价值]
Ann Dermatol Venereol. 2008 Jun-Jul;135(6-7):461-5. doi: 10.1016/j.annder.2007.12.017. Epub 2008 Jun 19.
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Acute generalized exanthematous pustulosis due to tetrazepam.
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Blue dyes, blue people: the systemic effects of blue dyes when administered via different routes.
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J Emerg Nurs. 2007 Apr;33(2):172-4. doi: 10.1016/j.jen.2006.11.007. Epub 2007 Feb 9.
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Am J Surg. 2007 Jan;193(1):122-4. doi: 10.1016/j.amjsurg.2006.03.013.
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Clinical heterogeneity of drug hypersensitivity.药物超敏反应的临床异质性。
Toxicology. 2005 Apr 15;209(2):123-9. doi: 10.1016/j.tox.2004.12.022.
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Recent development of sentinel lymph node biopsy for breast cancer in Japan.日本乳腺癌前哨淋巴结活检的最新进展
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Methylene blue: an effective treatment for contrast medium-induced anaphylaxis.亚甲蓝：一种治疗造影剂诱导的过敏反应的有效方法。
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