Sreenivas S Durga, Rao Akula Sreenivasa, Satyavani S Sri, Reddy Bavigadda Harish, Vasudevan Sanjay
Department of Oral and Maxillofacial Surgery, MNR Dental College and Hospital, Sangareddy, Andhra Pradesh, India.
J Indian Soc Periodontol. 2011 Jul;15(3):199-204. doi: 10.4103/0972-124X.85660.
It is dentists' dream to achieve bone repair with predictability, but without donor site morbidity as well as reconstruction of injured or pathologically damaged complex dental structures, however, this will no longer be a dream as these are being made into a reality using stem cell science. Stem cell science is clearly an intriguing and promising area of science. Stem cells have been isolated from a variety of embryonic and adult tissues. Dental stem cells are multipotent mesenchymal stem cells (MSCs) brought new enthusiasm among the researchers because of their easy accessibility, high quality and they don't pose the same ethical concerns and controversy in comparison with embryonic stem cells. This review article provides brief insights about stem cell basics, the state of art in human dental stem cell research and its possible impact on future dentistry. Even though most of these modalities are still in infancy, it is evident that the 21(st) century dentist is going to play a critical role in the field of medicine. The aim of this article is to bring awareness among the dentists about the huge potential associated with the use of stem cells in a clinical setting, as well as proper understanding of related problems.
实现可预测的骨修复，同时避免供体部位的并发症，并重建受损或病理损伤的复杂牙齿结构，这是牙医们的梦想。然而，随着干细胞科学将这些变为现实，这将不再是一个梦想。干细胞科学显然是一个引人入胜且充满希望的科学领域。干细胞已从多种胚胎组织和成人组织中分离出来。牙干细胞是多能间充质干细胞（MSCs），因其易于获取、质量高，且与胚胎干细胞相比不存在同样的伦理问题和争议，从而在研究人员中引发了新的热情。这篇综述文章简要介绍了干细胞的基础知识、人类牙干细胞研究的现状及其对未来牙科可能产生的影响。尽管这些方法大多仍处于起步阶段，但很明显，21世纪的牙医将在医学领域发挥关键作用。本文旨在提高牙医对在临床环境中使用干细胞的巨大潜力的认识，以及对相关问题的正确理解。
