Department of Health and Exercise Science, The University of Oklahoma, Norman, OK 73019-0615, USA.
Med Hypotheses. 2012 Jan;78(1):151-4. doi: 10.1016/j.mehy.2011.10.014. Epub 2011 Nov 1.
Venous blood flow restriction (VBFR) combined with low intensity resistance exercise (20-30% concentric 1-RM) has been observed to result in skeletal muscle hypertrophy, increased strength, and increased endurance. Knowledge of the mechanisms behind the benefits seen with VBFR is incomplete, but the benefits have traditionally been thought to occur from the decreased oxygen and accumulation of metabolites. Although many of the proposed mechanisms appear valid and are likely true with VBFR combined with resistance exercise, there are certain situations in which benefits are observed without a large accumulation of metabolites and/or large increases in fast twitch fiber type recruitment. Cell swelling appears to be a likely mechanism that appears to be present throughout all studies. VBFR may be able to induce cell swelling through a combination of blood pooling, accumulation of metabolites, and reactive hyperemia following the removal of VBFR which may contribute to skeletal muscle adaptations that occur with VBFR. We hypothesize that cell swelling is important for muscle growth and strength adaptation but when coupled with higher metabolic accumulation, this adaptation is even greater.
静脉血流限制（VBFR）与低强度抗阻运动（20-30% 向心 1-RM）相结合，已被观察到可导致骨骼肌肥大、力量增加和耐力增强。尽管 VBFR 背后的作用机制尚不完全清楚，但传统上认为这些益处来自于氧气减少和代谢物积累。虽然许多提出的机制似乎是合理的，并且在与抗阻运动相结合的 VBFR 中可能是正确的，但在某些情况下，即使没有大量代谢物积累和/或快速抽搐纤维类型募集的大量增加，也能观察到益处。细胞肿胀似乎是一种可能的机制，似乎存在于所有研究中。VBFR 可能通过血液蓄积、代谢物积累以及 VBFR 去除后的反应性充血来诱导细胞肿胀，这可能有助于 VBFR 引起的骨骼肌适应。我们假设细胞肿胀对于肌肉生长和力量适应很重要，但当与更高的代谢物积累结合时，这种适应会更大。
