植物中的 sn-甘油-3-磷酸酰基转移酶。
sn-Glycerol-3-phosphate acyltransferases in plants.
机构信息
Agricultural Lipid Biotechnology Program, Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
出版信息
Plant Signal Behav. 2011 Nov;6(11):1695-9. doi: 10.4161/psb.6.11.17777. Epub 2011 Nov 1.
Abstract
sn-Glycerol-3-phosphate acyltransferase (GPAT) catalyzes the acylation at sn-1 position of glycerol-3-phosphate to produce lysophosphatidic acid (LPA). LPA is an important intermediate for the formation of different types of acyl-lipids, such as extracellular lipid polyesters, storage and membrane lipids. Three types of GPAT have been found in plants, localizing to the plastid, endoplasmic reticulum, and mitochondria. These GPATs are involved in several lipid biosynthetic pathways and play important biological roles in plant development. In the present review, we will focus on the recent progress in studying the physiological functions of GPATs and their metabolic roles in glycerolipid biosynthesis.
摘要
sn-甘油-3-磷酸酰基转移酶 (GPAT) 催化甘油-3-磷酸 sn-1 位的酰化反应，生成溶血磷脂酸 (LPA)。LPA 是形成不同类型酰基脂质的重要中间体，如细胞外脂质聚酯、储存和膜脂质。在植物中已发现三种类型的 GPAT，定位于质体、内质网和线粒体。这些 GPAT 参与几种脂质生物合成途径，并在植物发育中发挥重要的生物学作用。在本综述中，我们将重点介绍研究 GPAT 生理功能及其在甘油磷脂生物合成中的代谢作用的最新进展。
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