Warren Alpert Medical School, Brown University, USA.
Menopause. 2012 Apr;19(4):413-9. doi: 10.1097/gme.0b013e318230f531.
The aim of this study was to examine the individual and combined associations of leisure-time physical activity and sleep with cardiovascular risk factors in postmenopausal women.
We analyzed 48-month cross-sectional follow-up data from 393 participants of the Women on the Move Through Activity and Nutrition Study, a behavioral weight loss trial. Leisure-time physical activity data were collected with the past-year Modifiable Activity Questionnaire, whereas sleep data were collected with the Pittsburgh Sleep Quality Index. We compared physical activity and sleep categories using analysis of variance, post hoc Scheffe tests, and multivariate analyses based on groups above/below the median leisure-time physical activity level, above/below the sleep quality value of 5, and above/below the sleep duration of 7 hours/day.
The average sleep quality and sleep duration did not significantly differ between women with high and women with low physical activity levels. When women with good sleep quality were compared, higher physical activity levels were associated with lower body mass index (2.0 kg/m; 25, 75 quartiles, 0.3, 3.6), waist circumference (6.3 cm; 1.7, 10.9), and total body fat (2.1%; 0.3, 4.0; P < 0.05). When participants with poor sleep quality were compared, highly active women had lower trunk fat, total body fat, and insulin levels than less active women did (P < 0.05). In multivariate analysis, physical activity was significantly associated with high-density lipoprotein level, trunk fat, and total body fat after controlling for sleep quality, sleep duration, age, hormone therapy and smoking status, and body mass index.
The combined associations of leisure-time physical activity and sleep suggest that cardiovascular risk factors are more favorable in highly active women relative to less active women regardless of sleep.
本研究旨在探讨绝经后女性的闲暇时间体力活动和睡眠与心血管危险因素的个体和综合关联。
我们分析了来自女性通过活动和营养研究（Women on the Move Through Activity and Nutrition Study）的 393 名参与者的 48 个月的横断面随访数据，这是一项行为减肥试验。闲暇时间体力活动数据通过过去一年的可修改活动问卷收集，而睡眠数据通过匹兹堡睡眠质量指数收集。我们使用方差分析、事后 Scheffe 检验以及基于中位数以上/以下闲暇时间体力活动水平、睡眠质量值 5 以上/以下以及睡眠时间 7 小时/天以上/以下的组的多元分析比较了体力活动和睡眠类别。
高体力活动水平和低体力活动水平的女性之间的平均睡眠质量和睡眠持续时间没有显著差异。当比较睡眠质量较好的女性时，较高的体力活动水平与较低的体重指数（2.0kg/m；25、75 四分位数，0.3、3.6）、腰围（6.3cm；1.7、10.9）和体脂肪总量（2.1%；0.3、4.0；P<0.05）相关。当比较睡眠质量较差的参与者时，高体力活动的女性与低体力活动的女性相比，躯干脂肪、体脂肪总量和胰岛素水平较低（P<0.05）。在多元分析中，在控制睡眠质量、睡眠持续时间、年龄、激素治疗和吸烟状况以及体重指数后，体力活动与高密度脂蛋白水平、躯干脂肪和体脂肪总量显著相关。
闲暇时间体力活动和睡眠的综合关联表明，无论睡眠如何，心血管危险因素在高体力活动的女性中更为有利。
