Division of Gastroenterology and Hepatology, Department of Medicine, School of Medicine, University of Utah, 30 North 1900 East, SOM 4R118, Salt Lake City, UT 84132-2410, USA.
Dig Dis Sci. 2012 Apr;57(4):1064-8. doi: 10.1007/s10620-011-1964-8. Epub 2011 Nov 12.
Anomalous pancreaticobiliary junction (APBJ) is the term used to describe anatomical variants of pancreatic and biliary ductal junctional anatomy. Patients have junction of the pancreatic and bile ducts located outside the duodenal wall, forming a long common channel. We report our findings and clinical outcomes in a North American series of patients with APBJ undergoing ERCP.
Retrospective chart review.
We reviewed 2,218 ERCP performed on 1,050 patients. Twelve patients (1.1%) with APBJ were identified (5F, 7M). No patient had an associated choledochocele. Mean age was 53.2 (range 17-85). A total of 43 ERCP procedures were performed on these 12 patients. All patients experienced passive pancreatography. No patient developed post-ERCP pancreatitis. Only one patient had a history of antecedent pancreatitis.
In North American patients undergoing ERCP, 1.1% of patients had APBJ. Our study population was predominately Caucasian, male, and in all but one patient lacked a history of prior pancreatitis. No patient developed post-ERCP pancreatitis. This suggests that APBJ may have different clinical manifestations in a North American population when compared to Asian populations.
异常胰胆管连接(APBJ)是用来描述胰胆管连接解剖结构变异的术语。患者的胰胆管连接位于十二指肠壁外,形成一个长的共同通道。我们报告了在接受 ERCP 的一组北美 APBJ 患者中的发现和临床结果。
回顾性图表审查。
我们回顾了在 1050 名患者中进行的 2218 次 ERCP。在 12 名(1.1%)APBJ 患者中发现了(5 名女性,7 名男性)。没有患者伴有胆总管囊肿。平均年龄为 53.2 岁(范围 17-85 岁)。这 12 名患者共进行了 43 次 ERCP 检查。所有患者均进行了被动胰管造影。没有患者发生 ERCP 后胰腺炎。只有一名患者有胰腺炎病史。
在接受 ERCP 的北美患者中,1.1%的患者存在 APBJ。我们的研究人群主要为白种人,男性,除 1 名患者外,均无既往胰腺炎病史。没有患者发生 ERCP 后胰腺炎。这表明与亚洲人群相比,APBJ 在北美人群中的临床表现可能不同。