Centre for Sustainable Pest and Disease Management, Rothamsted Research, Harpenden, Herts, AL5 2JQ, UK.
BMC Bioinformatics. 2011 Nov 15;12:447. doi: 10.1186/1471-2105-12-447.
Acquiring and exploring whole genome sequence information for a species under investigation is now a routine experimental approach. On most genome browsers, typically, only the DNA sequence, EST support, motif search results, and GO annotations are displayed. However, for many species, a growing volume of additional experimental information is available but this is rarely searchable within the landscape of the entire genome. •
We have developed a generic software which permits users to view a single genome in entirety either within its chromosome or supercontig context within a single window. This software permits the genome to be displayed at any scales and with any features. Different data types and data sets are displayed onto the genome, which have been acquired from other types of studies including classical genetics, forward and reverse genetics, transcriptomics, proteomics and improved annotation from alternative sources. In each display, different types of information can be overlapped, then retrieved in the desired combinations and scales and used in follow up analyses. The displays generated are of publication quality. •
OmniMapFree provides a unified, versatile and easy-to-use software tool for studying a single genome in association with all the other datasets and data types available for the organism.
获取和探索研究物种的全基因组序列信息现在是一种常规的实验方法。在大多数基因组浏览器上，通常只显示 DNA 序列、EST 支持、 motif 搜索结果和 GO 注释。然而，对于许多物种，越来越多的额外实验信息可用，但在整个基因组的范围内很少能够搜索到这些信息。
我们开发了一种通用软件，允许用户在单个窗口内按染色体或超级contig 上下文查看整个基因组。该软件允许在任何比例尺下显示基因组，并具有任何特征。不同类型和数据集的数据被显示在基因组上，这些数据是从其他类型的研究中获得的，包括经典遗传学、正向和反向遗传学、转录组学、蛋白质组学以及来自替代来源的改进注释。在每种显示中，不同类型的信息可以重叠，然后按所需的组合和比例尺检索，并用于后续分析。生成的显示具有出版质量。
OmniMapFree 为研究单个基因组与该生物体可用的所有其他数据集和数据类型提供了一个统一、通用且易于使用的软件工具。
