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美国成年人中幽门螺杆菌血清阳性率的长期趋势:持续存在的种族/民族差异的证据。

Secular trends in Helicobacter pylori seroprevalence in adults in the United States: evidence for sustained race/ethnic disparities.

机构信息

Division of Infectious Diseases, Brigham and Women’s Hospital, Boston, Massachusetts, USA.

出版信息

Am J Epidemiol. 2012 Jan 1;175(1):54-9. doi: 10.1093/aje/kwr288. Epub 2011 Nov 15.

DOI:10.1093/aje/kwr288
PMID:22085628
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3244610/
Abstract

Helicobacter pylori seroprevalence levels in US adults participating in the continuous National Health and Nutrition Examination Survey (1999-2000) increased with age in all racial/ethnic groups, with significantly higher age-standardized levels in Mexican Americans (64.0%, 95% confidence interval (CI): 58.8, 69.2) and non-Hispanic blacks (52.0%, 95% CI: 48.3, 55.7) compared with non-Hispanic whites (21.2%, 95% CI: 19.1, 23.2). Although seroprevalence levels remained similar to those found in National Health and Nutrition Examination Surveys from 1988 to 1991 among non-Hispanic blacks and Mexican Americans, they were significantly lower in non-Hispanic whites, especially at older ages. The factors driving the decline in H. pylori seroprevalence appear to be acting preferentially on the non-Hispanic white population.

摘要

在美国成年人中,参与持续的国家健康和营养检查调查(1999-2000 年)的幽门螺杆菌血清阳性率随着年龄的增长而在所有种族/族裔群体中增加,墨西哥裔美国人(64.0%,95%置信区间(CI):58.8,69.2)和非西班牙裔黑人(52.0%,95%CI:48.3,55.7)的年龄标准化水平明显更高,而非西班牙裔白人(21.2%,95%CI:19.1,23.2)。尽管非西班牙裔黑人和墨西哥裔美国人的血清阳性率与 1988 年至 1991 年的国家健康和营养检查调查中发现的水平相似,但在非西班牙裔白人中,这些水平明显较低,尤其是在年龄较大时。导致幽门螺杆菌血清阳性率下降的因素似乎优先作用于非西班牙裔白人。

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