自主神经功能障碍作为急性乙二醇摄入的迟发性后遗症：病例报告及文献复习。
Autonomic dysfunction as a delayed sequelae of acute ethylene glycol ingestion : a case report and review of the literature.
机构信息
Department of Medicine, Division of Nephrology and Hypertension, Nassau University Medical Center, NY 11554, USA.
出版信息
J Med Toxicol. 2012 Jun;8(2):124-9. doi: 10.1007/s13181-011-0195-x.
Abstract
Ethylene glycol poisoning is a common form of poisoning worldwide. The clinical course of ethylene glycol poisoning usually follows a three-stage progression, although these stages may overlap. A fourth stage of delayed neurological dysfunction consisting of cranial neuropathies has been suggested in several case reports. We describe a patient with unique findings of postural hypotension and gastroparesis following ethylene glycol toxicity with the additional uncommon features of albuminocytologic dissociation and increased intracranial pressure with papilledema. In addition, we provide a review of the literature on delayed neurological manifestations in ethylene glycol toxicity and further elucidate a description of a fourth stage of delayed neurological dysfunction following ethylene glycol poisoning.
摘要
乙二醇中毒是一种常见的全球性中毒形式。乙二醇中毒的临床过程通常遵循三阶段进展，尽管这些阶段可能会重叠。在几例病例报告中，还提出了第四阶段延迟性神经功能障碍，包括颅神经病变。我们描述了一例患者在乙二醇毒性后出现独特的体位性低血压和胃轻瘫表现，并有白蛋白细胞分离和颅内压增高伴视乳头水肿等不常见特征。此外，我们还回顾了关于乙二醇中毒延迟性神经表现的文献，并进一步阐述了乙二醇中毒后第四阶段延迟性神经功能障碍的描述。
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