Rostami Mojtaba, Javadi Abbas-Ali, Khorvash Farzin, Mostafavizadeh Kamyar, Adibi Atoosa, Babak Anahita, Ataei Behrooz, Meidani Mohsen, Naeini Alireza Emami, Salehi Hasan, Avijgan Majid, Yazdani Mohammad Reza, Rezaei Farshid
Isfahan Infectious Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
J Res Med Sci. 2011 May;16(5):591-7.
Pandemic 2009 H1N1 influenza A virus arrived at Isfahan in August 2009. The virus is still circulating in the world. The abnormal thoracic computerized tomographic (CT) scan findings vary widely among the studies of 2009 H1N1 influenza. We evaluated the thoracic CT findings in patients with 2009 H1N1 virus infection to describe findings compared to previously reported findings, and to suggest patterns that may be suggestive for 2009 influenza A (H1N1) in an appropriate clinical setting.
Retrospectively, the archive of all patients with a diagnosis of 2009 H1N1 influenza A were reviewed, in Al-Zahra Hospital in Isfahan, central Iran, between September 23(rd) 2009 to February 20(th) 2010. Out of 216 patients with confirmed 2009 influenza A (H1N1) virus, 26 cases with abnormal CT were enrolled in the study. Radiologic findings were characterized by the type and pattern of opacities and zonal distribution.
Patchy infiltration (34.6%), lobar consolidation (30.8%), and interstitial infiltration (26.9%) with airbronchogram (38.5%) were the predominant findings in our patients. Bilateral distribution was seen in 80.8% of the patients. Only one patient (3.8%) showed ground-glass opacity, predominant radiographic finding in the previous reports and severe acute respiratory syndrome (SARS).
The most common thoracic CT findings in pandemic H1N1 were patchy infiltration, lobar consolidation, and interstitial infiltration with airbronchogram and bilateral distribution. While these findings can be associated with other infections; they may be suggestive to 2009 influenza A (H1N1) in the appropriate clinical setting. Various radiographic patterns can be seen in thoracic CT scans of the influenza patients. Imaging findings are nonspecific.
2009年甲型H1N1流感大流行病毒于2009年8月抵达伊斯法罕。该病毒仍在全球传播。在2009年甲型H1N1流感的研究中，胸部计算机断层扫描（CT）异常表现差异很大。我们评估了2009年甲型H1N1病毒感染患者的胸部CT表现，以描述与先前报道的表现相比的结果，并提出在适当临床环境中可能提示2009年甲型H1N1流感的模式。
回顾性分析2009年9月23日至2010年2月20日期间伊朗中部伊斯法罕的Al-Zahra医院所有诊断为2009年甲型H1N1流感的患者档案。在216例确诊为2009年甲型H1N1流感病毒的患者中，26例CT异常的患者纳入研究。放射学表现以不透明度的类型和模式以及区域分布为特征。
斑片状浸润（34.6%）、肺叶实变（30.8%）和间质浸润（26.9%）伴空气支气管征（38.5%）是我们患者的主要表现。80.8%的患者表现为双侧分布。只有1例患者（3.8%）表现为磨玻璃影，这是先前报道和严重急性呼吸综合征（SARS）中主要的影像学表现。
大流行甲型H1N1流感最常见的胸部CT表现为斑片状浸润、肺叶实变、间质浸润伴空气支气管征及双侧分布。虽然这些表现可能与其他感染有关；但在适当的临床环境中可能提示2009年甲型H1N1流感。流感患者的胸部CT扫描可出现多种影像学模式。影像学表现不具有特异性。
