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砂拉越高尿酸血症患者概况。

A profile of gout patients in Sarawak.

机构信息

Unit of Rheumatology, Department of Medicine, Sarawak General Hospital, Jalan Hospital, 93450 Kuching, Sarawak, East Malaysia.

出版信息

Rheumatol Int. 2013 Apr;33(4):1079-82. doi: 10.1007/s00296-011-2245-8. Epub 2011 Nov 19.

Abstract

We performed a prospective study of all patients diagnosed with gout and who received treatment in Sarawak General Hospital from 1 July 2010 to 31 December 2010. There was a total of 138 patients in our study of which 92 (66.7%) were from the indigenous populations. They have a mean age of 56.5 ± 12.5 years with a mean duration of illness of 11.6 ± 8.7 years. The mean lag time between symptom onset to the diagnosis of gout was 2.8 ± 4.8 years and a mean lag time to appropriate treatment of gout of 8.8 ± 8.4 years. Sixty-six (47.8%) patients have family history of gout. The common complications of gout in our patients were tophi (47.1%), joint deformities (39.1%), kidney stones (16.7%), and uric acid nephropathy (0.7%). Hospitalization occurred in 93 (67.4%) patients. Gout is a serious medical problem in our centre. Gout affects middle-aged men, especially the indigenous populations. Almost half of our patients have a family history of gout and have tophi formations. Our gout patients have a significant delay in diagnosis and appropriate treatment, thus contributing to more complications and hospitalizations in our centre. There is an urgent need to educate both patients and healthcare workers on gout and its treatment to reduce the burden of chronic gout in Sarawak.

摘要

我们对 2010 年 7 月 1 日至 12 月 31 日期间在砂拉越综合医院接受治疗的所有痛风患者进行了前瞻性研究。我们的研究共有 138 名患者,其中 92 名(66.7%)来自土著居民。他们的平均年龄为 56.5 ± 12.5 岁,平均患病时间为 11.6 ± 8.7 年。从症状出现到痛风确诊的平均潜伏期为 2.8 ± 4.8 年,从痛风确诊到接受适当治疗的平均潜伏期为 8.8 ± 8.4 年。66 名(47.8%)患者有痛风家族史。我们患者的常见痛风并发症包括痛风石(47.1%)、关节畸形(39.1%)、肾结石(16.7%)和尿酸肾病(0.7%)。93 名(67.4%)患者住院治疗。痛风是我们中心的一个严重医疗问题。痛风影响中年男性,尤其是土著居民。我们近一半的患者有痛风家族史,并有痛风石形成。我们的痛风患者在诊断和适当治疗方面存在明显的延迟,这导致我们中心出现更多的并发症和住院治疗。我们迫切需要对痛风及其治疗方法进行教育,以减轻砂拉越慢性痛风的负担。

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