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波多黎各女性对遗传性乳腺癌和卵巢癌综合征的遗传咨询与检测的知识及兴趣的初步研究。

A pilot study of knowledge and interest of genetic counseling and testing for hereditary breast and ovarian cancer syndrome among Puerto Rican women.

作者信息

Vadaparampil Susan T, Quinn Gwendolyn P, Dutil Julie, Puig Marieva, Malo Teri L, McIntyre Jessica, Perales Rossybelle, August Euna M, Closser Zuheily

机构信息

Health Outcomes and Behavior Program, Moffitt Cancer Center, 12902 Magnolia Drive, MRC CANCONT, Tampa, FL, 33612, USA,

出版信息

J Community Genet. 2011 Dec;2(4):211-21. doi: 10.1007/s12687-011-0058-9. Epub 2011 Jul 12.

DOI:10.1007/s12687-011-0058-9
PMID:22109874
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3215781/
Abstract

This study explored baseline levels of knowledge and attitude toward genetic testing (GT) for hereditary breast and ovarian cancer among Puerto Rican women. A secondary aim was to evaluate whether these factors differed between respondents in Puerto Rico and Tampa. Puerto Rican women with a personal or family history of breast or ovarian cancer who live in Puerto Rico (n = 25) and Tampa (n = 20) were interviewed. Both groups were interested in obtaining GT; women living in Puerto Rico were more likely to report they would get GT within 6 months (p = 0.005). The most commonly cited barrier was cost; the most commonly cited facilitator was provider recommendation. There was no difference in overall knowledge between Tampa (M = 5.15, SD = 1.63) and Puerto Rico (M = 5.00, SD = 1.87) participants (p = 0.78). Involving health care providers in recruitment and highlighting that GT may be available at minimal or no cost in the USA and Puerto Rico may facilitate participation.

摘要

本研究探讨了波多黎各女性对遗传性乳腺癌和卵巢癌基因检测(GT)的知识和态度基线水平。次要目的是评估这些因素在波多黎各和坦帕的受访者之间是否存在差异。对居住在波多黎各(n = 25)和坦帕(n = 20)且有个人或家族乳腺癌或卵巢癌病史的波多黎各女性进行了访谈。两组都对进行基因检测感兴趣;居住在波多黎各的女性更有可能报告她们会在6个月内进行基因检测(p = 0.005)。最常提到的障碍是费用;最常提到的促进因素是医生推荐。坦帕(M = 5.15,标准差 = 1.63)和波多黎各(M = 5.00,标准差 = 1.87)的参与者在总体知识方面没有差异(p = 0.78)。让医疗保健提供者参与招募,并强调在美国和波多黎各基因检测可能只需很少费用或免费,这可能会促进参与。

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