孕期的母体行为会影响后代患肥胖症的风险。
Maternal behaviors during pregnancy impact offspring obesity risk.
作者信息
Phelan Suzanne, Hart Chantelle, Phipps Maureen, Abrams Barbara, Schaffner Andrew, Adams Angelica, Wing Rena
机构信息
Kinesiology Department, California Polytechnic State University, 1 Grand Avenue, San Luis Obispo, CA 93407-0386, USA.
出版信息
Exp Diabetes Res. 2011;2011:985139. doi: 10.1155/2011/985139. Epub 2011 Oct 26.
This study investigated the effects of maternal changes during pregnancy in diet, exercise, and psychosocial factors on offspring weight parameters at birth and 6 months. In overweight/obese (OW/OB; n = 132) mothers, greater % kcal from sweets early in pregnancy was the strongest, independent predictor of higher weight for age (WFA) (beta = 0.19; P = 0.004), higher odds of macrosomia (OR = 1.1 (1.0-1.2); P = 0.004) and WFA >90th percentile at birth (OR = 1.2 (1.1-1.3); P = 0.002) and higher WFA at 6 months (beta = 0.30; P = 0.002). In normal weight (n = 153) mothers, higher intake of soft drinks was the strongest predictor of higher offspring WFA at birth (beta = 0.16; P = 0.04) but not at 6 months. Prenatal physical activity, depressive symptoms, and sleep-related variables did not significantly predict offspring weight outcomes. Mothers' eating behaviors during pregnancy, especially intake of sweets in OW/OB mothers, may have a lasting effect on child weight.
本研究调查了孕期母亲在饮食、运动和心理社会因素方面的变化对后代出生时及6个月时体重参数的影响。在超重/肥胖（OW/OB；n = 132）母亲中，孕期早期来自甜食的热量百分比越高，是年龄别体重（WFA）较高的最强独立预测因素（β = 0.19；P = 0.004），巨大儿几率较高（OR = 1.1（1.0 - 1.2）；P = 0.004），出生时WFA>第90百分位数的几率较高（OR = 1.2（1.1 - 1.3）；P = 0.002），以及6个月时WFA较高（β = 0.30；P = 0.002）。在正常体重（n = 153）母亲中，较高的软饮料摄入量是后代出生时较高WFA的最强预测因素（β = 0.16；P = 0.04），但在6个月时并非如此。产前身体活动、抑郁症状和与睡眠相关的变量并未显著预测后代体重结果。母亲孕期的饮食行为，尤其是OW/OB母亲的甜食摄入量，可能对儿童体重有持久影响。
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