Hennis Anselm J M, Hambleton Ian R, Wu Suh-Yuh, Skeete Desiree H-A, Nemesure Barbara, Leske M Cristina
Chronic Disease Research Centre, The University of the West Indies, Jemmott's Lane, St. Michael, Barbados.
Prostate Cancer. 2011;2011:565230. doi: 10.1155/2011/565230. Epub 2011 Apr 17.
We describe prostate cancer incidence and mortality in Barbados, West Indies. We ascertained all histologically confirmed cases of prostate cancer during the period July 2002 to December 2008 and reviewed each death registration citing prostate cancer over a 14-year period commencing January 1995. There were 1101 new cases for an incidence rate of 160.4 (95% Confidence Interval: 151.0-170.2) per 100,000 standardized to the US population. Comparable rates in African-American and White American men were 248.2 (95% CI: 246.0-250.5) and 158.0 (95% CI: 157.5-158.6) per 100,000, respectively. Prostate cancer mortality rates in Barbados ranged from 63.2 to 101.6 per 100,000, compared to 51.1 to 78.8 per 100,000 among African Americans. Prostate cancer risks are lower in Caribbean-origin populations than previously believed, while mortality rates appeared to be higher than reported in African-American men. Studies in Caribbean populations may assist understanding of disparities among African-origin populations with shared heredity.
我们描述了西印度群岛巴巴多斯的前列腺癌发病率和死亡率。我们确定了2002年7月至2008年12月期间所有经组织学确诊的前列腺癌病例，并回顾了从1995年1月开始的14年期间每例因前列腺癌死亡的登记情况。共有1101例新病例，发病率为每10万人160.4例（95%置信区间：151.0 - 170.2），以美国人口为标准进行标准化。非裔美国男性和美国白人男性的可比发病率分别为每10万人248.2例（95%置信区间：246.0 - 250.5）和158.0例（95%置信区间：157.5 - 158.6）。巴巴多斯的前列腺癌死亡率为每10万人63.2至101.6例，相比之下，非裔美国人的死亡率为每10万人51.1至78.8例。加勒比裔人群的前列腺癌风险低于此前的认知，而死亡率似乎高于非裔美国男性的报告水平。对加勒比人群的研究可能有助于理解具有共同遗传背景的非洲裔人群之间的差异。
