Unité d'Etude du Mouvement, FNRS, ULB Erasme Neurologie, 808 Route de Lennik, Brussels, Belgium.
Cerebellum. 2012 Jun;11(2):446-8. doi: 10.1007/s12311-011-0336-4.
Numerous laboratories currently focus their activities on cerebellar research. The cerebellum is attractive due to its sophisticated circuitry, high degree of modifiability combined with unique operational mechanisms, and the growing awareness of its multiple roles. Works of pioneers of these last two centuries, such as Rolando, Flourens, Magendie, Luciani, Lugaro, Babinski, Holmes, Cajal, Larsell, Eccles, Voogd, Llinas, or Ito, still exert a strong influence in the way we investigate cerebellar functions. The amount of knowledge is exploding, thanks to advances in genetics, molecular and cellular analyses, profusion of brain imaging techniques, novel behavioral assessments, and reshaping of models of cerebellar function. More than ever, strong and consistent intellectual efforts are required to generate homogeneous research outcomes that might exert a significant influence in the forthcoming domains of research. Because research is often based on the results of our predecessors, The Cerebellum has launched a section called Cerebellar Classics. Papers selected represent key steps for the discovery of some of the secrets of the cerebellar circuitry. These seminal contributions offer a portal to the past to modern scholars.
目前，许多实验室都专注于小脑研究。小脑因其复杂的电路、高度的可修饰性与独特的运作机制，以及其多重作用的不断被认识，而具有吸引力。过去两个世纪的先驱者们的工作，如 Rolando、Flourens、Magendie、Luciani、Lugaro、Babinski、Holmes、Cajal、Larsell、Eccles、Voogd、Llinas 或 Ito 的工作，仍然在我们研究小脑功能的方式上产生着强烈的影响。由于遗传学、分子和细胞分析的进步、大量的脑成像技术、新的行为评估方法，以及小脑功能模型的重塑，知识呈爆炸式增长。为了产生可能在即将到来的研究领域产生重大影响的同质研究成果，需要付出强烈而一致的智力努力。由于研究往往基于我们前人的成果，《小脑》杂志推出了一个名为“小脑经典”的栏目。所选的论文代表了发现小脑电路某些秘密的关键步骤。这些开创性的贡献为现代学者提供了一个通往过去的门户。
