Vestergaard B F, Norrild B
IARC Sci Publ (1971). 1978(24 Pt 1):225-34.
Crossed immunoelectrophoresis of Triton X-100 solubilized HSV-infected cells has identified several major HSV glycoprotein antigens in the precipitating profile. Immunization of rabbits with the corresponding precipitates resulted in the production of monospecific antisera against the antigen part of the precipitate. The immunological importance of five different HSV glycoproteins in respect of their representation on the outer virion envelope as targets for neutralizing antibodies was evaluated by comparison of immunoprecipitating activity and neutralizing potency of the corresponding monospecific antisera.
对经Triton X - 100溶解的单纯疱疹病毒（HSV）感染细胞进行交叉免疫电泳，已在沉淀图谱中鉴定出几种主要的HSV糖蛋白抗原。用相应沉淀物免疫兔子，产生了针对沉淀物抗原部分的单特异性抗血清。通过比较相应单特异性抗血清的免疫沉淀活性和中和效力，评估了五种不同HSV糖蛋白在病毒体外包膜上作为中和抗体靶点的免疫学重要性。
