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树脂基复合材料中双酚 A 的释放及其对正畸舌侧保持器粘接性能的影响

Release of bisphenol A from resin composite used to bond orthodontic lingual retainers.

机构信息

Department of Orthodontics, Dental College, Kyung Hee University, Seoul, Korea.

出版信息

Am J Orthod Dentofacial Orthop. 2011 Dec;140(6):779-89. doi: 10.1016/j.ajodo.2011.04.022.

Abstract

INTRODUCTION

In this study, we assessed the changes in bisphenol A (BPA) levels in saliva and urine after placing lingual bonded retainers.

METHODS

Liquid chromatography/mass spectrometry was used to examine the BPA levels in the saliva and urine samples collected from 22 volunteers who received a lingual bonded retainer on their mandibular dentition. Samples were collected immediately before placement and 30 minutes, 1 day, 1 week, and 1 month after placement. The time elapsed after placement, type of resin composite (nanohybrid filled flowable resin or conventional hybrid resin), surface prophylaxis, age, and sex were evaluated for their effects on the BPA levels.

RESULTS

The only significant high level of BPA was observed in the saliva collected just after placement of the lingual bonded retainer. Age and sex did not affect the BPA levels. Subjects in the flowable resin group had lower BPA levels than those in the conventional hybrid resin group; pumice prophylaxis decreased the level of BPA released from the conventional hybrid resin at the immediate time point. The salivary BPA level (maximum, 20.889 ng/mL) detected in the samples collected just after placement was far lower than the reference daily intake dose.

CONCLUSIONS

Accordingly, the potential toxicity of BPA from placing lingual bonded retainer might be negligible. On the other hand, because the health-effective amount of BPA is controversial, BPA release should be minimized.

摘要

简介

本研究评估了在舌侧粘接保持器放置后唾液和尿液中双酚 A(BPA)水平的变化。

方法

采用液相色谱/质谱法检测 22 名志愿者下颌牙列接受舌侧粘接保持器后唾液和尿液样本中的 BPA 水平。在放置前、放置后 30 分钟、1 天、1 周和 1 个月采集样本。评估放置后时间、树脂复合材料类型(纳米复合流动树脂或传统混合树脂)、表面预防、年龄和性别对 BPA 水平的影响。

结果

仅在放置舌侧粘接保持器后立即采集的唾液中观察到 BPA 的高浓度。年龄和性别对 BPA 水平没有影响。流动树脂组的 BPA 水平低于传统混合树脂组;浮石预防在即刻时间点降低了传统混合树脂释放的 BPA 水平。放置后立即采集的样本中检测到的唾液 BPA 水平(最高值为 20.889ng/ml)远低于参考日摄入量。

结论

因此,放置舌侧粘接保持器产生的 BPA 的潜在毒性可能可以忽略不计。另一方面,由于 BPA 的有效健康剂量存在争议,应尽量减少 BPA 的释放。

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