Department of Anesthesiology and Pain Management, University Hospital Maastricht, Department of Neurology, University Hospital Maastricht, Clinical Epidemiology and Medical Technology Assessment, University Hospital Maastricht, the Netherlands, and Department of Anesthesiology, Critical Care and Multidisciplinary Pain Center, ZOL, Genk, Belgium.
Neuromodulation. 2003 Jan;6(1):6-14. doi: 10.1046/j.1525-1403.2003.03001.x.
Cervicogenic headache and cervicobrachialgia are frequent diagnoses of chronic cervical pain. After failure of conservative treatment, an interventional approach may be indicated in the absence of any indication for causal surgical treatment. The pulsed radiofrequency (PRF) technique exposes the nerve to a high-frequency electric field while the temperature of the electrode tip does not exceed 42°C. This method is thought to be nondestructive and almost free of neurologic side effects and complications. Our extended pilot study was performed to confirm the perceived efficacy of PRF for short- and long-term relief of chronic cervical pain. We carried out a clinical audit of the first 18 patients treated with PRF at the cervical dorsal root ganglion. An independent evaluator reviewed the medical records. Patients with good clinical results at 8 weeks were evaluated for long-term effect (> 6 months), based on a 7-point Likert scale. Thirteen patients (72%) showed short-term clinical success (≥ 50% pain relief). Mean follow-up was 19.4 months (SD 8.9 months), maximum 2.5 years. The duration of satisfactory pain relief (6 or 7 on the Likert scale) varied between 2 and over 30 months, with a mean duration of 9.2 months (SD 11.2 months). Kaplan-Meier analysis illustrated that 50% of patients experienced success 3 months after treatment. We could not identify predictive variables for clinical outcome. None of the patients reported post-treatment neuritis or other adverse events. To our knowledge, this is the first documented series of chronic cervical pain syndromes treated with PRF. Satisfactory pain relief of at least 50% was achieved in 13 of 18 (72%) patients at 8 weeks. More than one year after treatment, six patients (33%) continue to rate treatment outcome as good or very good. No side effects were reported. j.
颈源性头痛和颈臂痛是慢性颈痛的常见诊断。在保守治疗失败后,如果没有因果性手术治疗的指征,介入治疗可能是必要的。脉冲射频(PRF)技术在电极尖端温度不超过 42°C 的情况下,使神经暴露在高频电场中。这种方法被认为是非破坏性的,几乎没有神经副作用和并发症。我们进行了一项扩展的初步研究,以确认 PRF 对慢性颈痛的短期和长期缓解的疗效。我们对在颈椎背根神经节进行 PRF 治疗的前 18 名患者进行了临床审计。一名独立评估者审查了病历。在 8 周时临床结果良好的患者根据 7 分 Likert 量表评估长期疗效(>6 个月)。13 名患者(72%)表现出短期临床成功(≥50%疼痛缓解)。平均随访时间为 19.4 个月(SD 8.9 个月),最长随访时间为 2.5 年。满意的疼痛缓解持续时间(Likert 量表 6 或 7)在 2 至 30 个月之间变化,平均持续时间为 9.2 个月(SD 11.2 个月)。Kaplan-Meier 分析表明,治疗后 3 个月,50%的患者有成功的经验。我们无法确定临床结果的预测变量。没有患者报告治疗后神经炎或其他不良反应。据我们所知,这是第一组用 PRF 治疗的慢性颈痛综合征的记录。在 8 周时,18 名患者中有 13 名(72%)达到至少 50%的疼痛缓解。治疗 1 年后,6 名患者(33%)继续将治疗结果评为良好或非常好。没有报告任何副作用。