Department of Public Health, Section of Epidemiology, University of Aarhus, Bartholin allé 2, 8000, Århus C, Aarhus, Denmark.
J Autism Dev Disord. 2012 Aug;42(8):1717-28. doi: 10.1007/s10803-011-1416-5.
The aim of this study was to study patterns of contact with hospital for children with autism spectrum disorder (ASD) using Danish population based register data. We included all children born in Denmark from 1994 through 2002. We found that children diagnosed with ASD had an increased rate of contact with hospital, almost regardless of the cause for the hospital contact. Given the overall association between hospital contact for various causes and ASD observed in these data, hospital data should be used cautiously in future studies searching for associations between a specific disease and ASD. If the increased rate of hospital contact overall for children with ASD is not considered, then misleading over interpretations might be made of observed associations between specific diseases and ASD.
本研究旨在利用丹麦基于人群的登记数据研究自闭症谱系障碍(ASD)儿童的住院模式。我们纳入了 1994 年至 2002 年期间在丹麦出生的所有儿童。我们发现,被诊断为 ASD 的儿童无论其住院原因如何,其住院率均有增加。鉴于这些数据中观察到的各种原因导致的与 ASD 相关的住院率之间的总体关联,在未来研究中,在寻找特定疾病与 ASD 之间的关联时,应谨慎使用医院数据。如果不考虑 ASD 儿童整体住院率增加的情况,则可能会对观察到的特定疾病与 ASD 之间的关联产生误导性的过度解释。