Ino T, Shimazaki S, Akimoto K, Park I, Nishimoto K, Yabuta K, Tanaka A
Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan.
Pediatr Radiol. 1990;20(7):520-3. doi: 10.1007/BF02011380.
To evaluate the angiographic features of coronary lesions in Kawasaki disease with coronary artery calcification, cinefluoroscopy and cineangiography were retrospectively reviewed in 116 patients who had undergone coronary angiography between 1982 and 1989. Angiographic abnormalities of coronary arteries were demonstrated in 55 of the 116 patients. In 5 (9.1%) of the 55 patients, 9 with calcification were identified by cinefluoroscopy and chest x-ray. Eight of the 9 calcified lesions showed a circular or ring-shape configuration. Coronary angiography revealed a total occlusion of the right coronary artery with collateral circulation from the distal left coronary artery in 2 patients and a severe stenosis of the right coronary artery in 2 patients, in whom anticoagulant therapy had not been continued during the follow-up periods. The remaining patient in whom anticoagulant therapy had been continued had bilateral aneurysms but no significant stenosis. These results indicate that a ring-shape calcification on chest x-ray in a patient with a history of Kawasaki disease may suggest an involvement by coronary artery stenosis even when anticoagulant drugs had been given. Therefore, coronary angiography should be performed to evaluate the stenotic lesions if this type of calcification is found by routine radiographic examination.
为评估川崎病合并冠状动脉钙化患者冠状动脉病变的血管造影特征,我们回顾性分析了1982年至1989年间接受冠状动脉造影的116例患者的荧光电影摄影和血管造影资料。116例患者中55例显示冠状动脉造影异常。在这55例患者中的5例(9.1%),通过荧光电影摄影和胸部X线检查发现9处钙化。9处钙化病变中的8处呈圆形或环形。冠状动脉造影显示,2例患者右冠状动脉完全闭塞,有来自左冠状动脉远端的侧支循环,2例患者右冠状动脉严重狭窄,这2例患者在随访期间未持续进行抗凝治疗。持续进行抗凝治疗的其余1例患者有双侧动脉瘤,但无明显狭窄。这些结果表明,有川崎病病史的患者胸部X线显示环形钙化可能提示即使给予了抗凝药物仍存在冠状动脉狭窄。因此,如果通过常规影像学检查发现这种类型的钙化,应进行冠状动脉造影以评估狭窄病变。