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早期固体食物喂养与儿童复发性湿疹:一项10年纵向研究。

Early solid feeding and recurrent childhood eczema: a 10-year longitudinal study.

作者信息

Fergusson D M, Horwood L J, Shannon F T

机构信息

Department of Paediatrics, Christchurch School of Medicine, Christchurch Hospital, New Zealand.

出版信息

Pediatrics. 1990 Oct;86(4):541-6.

PMID:2216619
Abstract

The relationship between early solid feeding practices and risks of recurrent or chronic eczema in childhood was examined in a birth cohort of New Zealand children studied to the age of 10. By the age of 10 years, 7.5% of children had chronic or recurrent eczema. There were clear and consistent associations between the diversity of the child's diet during the first 4 months and risks of eczema. Even when due allowance was made for a range of confounding factors--including parental atopic illness, atopic illness in siblings, the child's early milk diet, and family social background--children exposed to four or more different types of solid food before 4 months had risks of recurrent or chronic eczema that were 2.9 times those of children who were not exposed to early solid feeding. It is concluded that early exposure to a diet diverse in potential food antigens may act to predispose susceptible children to recurrent or chronic childhood eczema.

摘要

在一项对新西兰儿童进行追踪研究至10岁的出生队列研究中,调查了早期固体食物喂养方式与儿童复发性或慢性湿疹风险之间的关系。到10岁时,7.5%的儿童患有慢性或复发性湿疹。在婴儿出生后的前4个月内,其饮食的多样性与湿疹风险之间存在明确且一致的关联。即使考虑了一系列混杂因素,包括父母的特应性疾病、兄弟姐妹的特应性疾病、婴儿早期的奶类饮食以及家庭社会背景等,在4个月前接触过四种或更多不同类型固体食物的儿童,其复发性或慢性湿疹的风险是未接触过早产固体食物儿童的2.9倍。研究得出结论,早期接触富含潜在食物抗原的多样化饮食可能会使易感儿童易患复发性或慢性儿童湿疹。

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