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生活方式活动与记忆:多样性可能是生活的调味品。妇女健康与衰老研究 II。

Lifestyle activities and memory: variety may be the spice of life. The women's health and aging study II.

机构信息

Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

出版信息

J Int Neuropsychol Soc. 2012 Mar;18(2):286-94. doi: 10.1017/S135561771100169X. Epub 2011 Dec 15.

Abstract

This study examined whether participation in a variety of lifestyle activities was comparable to frequent participation in cognitively challenging activities in mitigating impairments in cognitive abilities susceptible to aging in healthy, community-dwelling older women. Frequencies of participation in various lifestyle activities on the Lifestyle Activities Questionnaire (LAQ) were divided according to high (e.g., reading), moderate (e.g., discussing politics), and low (e.g., watching television) cognitive demand. We also considered the utility of participation in a variety of lifestyle activities regardless of cognitive challenge. Immediate and delayed verbal recall, psychomotor speed, and executive function were each measured at baseline and at five successive exams, spanning a 9.5-year interval. Greater variety of participation in activities, regardless of cognitive challenge, was associated with an 8 to 11% reduction in the risk of impairment in verbal memory and global cognitive outcomes. Participation in a variety of lifestyle activities was more predictive than frequency or level of cognitive challenge for significant reductions in risk of incident impairment on measures sensitive to cognitive aging and risk for dementia. Our findings offer new perspectives in promoting a diverse repertoire of activities to mitigate age-related cognitive declines.

摘要

本研究旨在探讨参与各种生活方式活动是否与频繁参与认知挑战性活动相当,从而减轻健康、社区居住的老年女性易受衰老影响的认知能力损伤。生活方式活动问卷(LAQ)中各种生活方式活动的参与频率根据认知需求的高低(例如阅读)、中(例如讨论政治)和低(例如看电视)进行划分。我们还考虑了无论认知挑战如何,参与各种生活方式活动的效用。在基线和连续五次检查时测量了即时和延迟言语回忆、心理运动速度和执行功能,跨越了 9.5 年的间隔。参与活动的多样性增加,无论认知挑战如何,与言语记忆和整体认知结果受损风险降低 8%至 11%相关。与认知挑战的频率或水平相比,参与各种生活方式活动更能预测对认知老化敏感的指标和痴呆风险的损伤发生率降低的风险。我们的研究结果为促进多样化的活动组合以减轻与年龄相关的认知衰退提供了新的视角。

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