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应用前节傅里叶域光学相干断层扫描对穿透性角膜移植术后周边前房角的非侵入性观察。

Noninvasive observations of peripheral angle in eyes after penetrating keratoplasty using anterior segment fourier-domain optical coherence tomography.

机构信息

Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan.

出版信息

Cornea. 2012 Mar;31(3):259-63. doi: 10.1097/ICO.0b013e318226daa9.

DOI:10.1097/ICO.0b013e318226daa9
PMID:22189595
Abstract

PURPOSE

To examine iridotrabecular contact (ITC) as a peripheral anterior synechia (PAS) of patients who underwent penetrating keratoplasty (PKP) using anterior segment Fourier-domain optical coherence tomography (OCT).

METHODS

Retrospective, observational case series. ITC, ITC index, and ITC area of 60 eyes of 52 patients who underwent PKP at the Department of Ophthalmology in the University of Tokyo Hospital (mean follow-up time 102.8 ± 116.1 months postoperation) were calculated using the angle analysis mode of a commercially available anterior segment Fourier-domain OCT system (CASIA; TOMEY, Nagoya, Japan). We analyzed the occurrence of ITC, ITC index, and ITC area with preoperative diagnosis, lens status, operation method, operation frequency, graft size, and intraocular pressure elevation.

RESULTS

ITC was observed in 28 (46.7%) of 60 eyes. Average ITC index was 14.0%, and average ITC area was 5.97 mm. ITC was significantly associated with eyes with bullous keratopathy, infectious keratitis, pseudophakia, PKP with cataract operation, several PKP operations, and large graft size.

CONCLUSIONS

Anterior segment Fourier-domain OCT is a useful and innovative tool that enables us to observe the anterior chamber angle and examine ITC as PAS of eyes with corneal opacity, even after PKP.

摘要

目的

使用前节傅里叶域光学相干断层扫描(OCT)检查穿透性角膜移植(PKP)术后患者的虹膜小梁接触(ITC)作为周边前粘连(PAS)。

方法

回顾性观察性病例系列。在东京大学医院眼科(平均术后随访时间 102.8±116.1 个月)对 52 例 60 只眼行 PKP 的患者使用商用前节傅里叶域 OCT 系统(CASIA;TOMEY,名古屋,日本)的角度分析模式计算 ITC、ITC 指数和 ITC 面积。我们分析了 ITC、ITC 指数和 ITC 面积与术前诊断、晶状体状态、手术方法、手术频率、移植物大小和眼压升高的关系。

结果

28 只眼(46.7%)观察到 ITC。平均 ITC 指数为 14.0%,平均 ITC 面积为 5.97mm。ITC 与大疱性角膜病变、感染性角膜炎、白内障术后、白内障手术联合 PKP、多次 PKP 手术和大移植物大小的眼显著相关。

结论

前节傅里叶域 OCT 是一种有用的创新工具,可用于观察前房角并检查角膜混浊患者的 ITC 作为 PAS,即使在 PKP 术后也可以。

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