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儿童早期 CT 辐射暴露:法国大规模多中心研究。

Radiation exposure from CT in early childhood: a French large-scale multicentre study.

机构信息

Epidemiology Department, Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.

出版信息

Br J Radiol. 2012 Jan;85(1009):53-60. doi: 10.1259/bjr/90758403.

DOI:10.1259/bjr/90758403
PMID:22190749
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3473922/
Abstract

OBJECTIVES

The increasing use of CT scans in the paediatric population raises the question of a possible health impact of ionising radiation exposure associated with CT scans. The aim of this study was to describe the pattern of CT use in early childhood.

METHODS

In 14 major French paediatric radiology departments, children undergoing at least 1 CT scan before age 5, between 2000 and 2006, were included. For each examination, absorbed organ doses were calculated.

RESULTS

43% of the 27 362 children in the cohort were aged less than 1 year during their first exposure, with 9% being aged less than 1 month. The mean number of examinations per child was 1.6 (range 1-43). The examinations included: head in 63% of the cases, chest in 21%, abdomen and pelvis in 8% and others in 8%. Brain and eye lenses received the highest cumulative doses from head examinations, with mean organ dose values of 22 mGy (maximum 1107 mGy) and 26 mGy (maximum 1392 mGy), respectively. The mean cumulative effective dose was 3.2 mSv (range 0.1-189 mSv).

CONCLUSION

CT scan exposure in childhood is responsible for relatively high doses to radiosensitive organs. The rather large dose range according to the protocols used requires their optimisation. The cohort follow-up will study the risk of long-term radiation-induced cancer.

摘要

目的

儿科人群中 CT 扫描的应用日益增多,这引发了人们对与 CT 扫描相关的电离辐射暴露可能对儿童健康造成影响的关注。本研究旨在描述儿童早期 CT 检查的应用模式。

方法

在法国 14 个主要儿科放射科部门,对 2000 年至 2006 年间至少接受过 1 次 CT 扫描且年龄小于 5 岁的儿童进行了研究。对每一检查,计算了受检器官的吸收剂量。

结果

队列中 43%的儿童首次 CT 扫描时年龄小于 1 岁,9%的儿童首次 CT 扫描时年龄小于 1 个月。每名儿童的平均检查次数为 1.6 次(范围 1-43 次)。检查包括:头颅检查占 63%,胸部检查占 21%,腹部和骨盆检查占 8%,其他部位检查占 8%。脑和眼晶体接受的来自头颅检查的累积剂量最高,平均器官剂量值分别为 22 mGy(最高值 1107 mGy)和 26 mGy(最高值 1392 mGy)。平均有效剂量累积值为 3.2 mSv(范围 0.1-189 mSv)。

结论

儿童 CT 扫描检查导致了对放射敏感器官的相对较高剂量。根据所用方案,剂量范围较大,需要对其进行优化。对该队列的随访将研究长期辐射诱发癌症的风险。

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