Virus Res. 2012 Mar;164(1-2):1-3. doi: 10.1016/j.virusres.2011.12.005. Epub 2011 Dec 14.
The discovery of porcine circovirus type 2 (PCV2) in 1998 initiated intensive research on arguably the most economically important pathogen facing the global swine industry today. PCV2 infection is now widespread worldwide, and increasing numbers of disease conditions have been linked to PCV2 infection in pigs. In this special issue of Virus Research, leading experts in the field review the history, epidemiology, transmission, clinical and pathological features, immunology, pathogenesis, molecular biology and vaccine development of PCV2 and porcine circovirus associated disease (PCVAD). In addition, circovirus-like DNA sequences recently identified from humans and other animal species and their biological significances are also reviewed. The articles in this special issue identify gaps in current PCV2 research and offer insights for the direction of future research.
猪圆环病毒 2 型（PCV2）于 1998 年被发现，自此之后，人们对这种目前全球养猪业面临的最重要的经济病原体展开了深入研究。PCV2 感染现已在全球广泛传播，越来越多的疾病与猪 PCV2 感染有关。本期病毒学研究特刊的主要专家回顾了 PCV2 及猪圆环病毒相关疾病（PCVAD）的历史、流行病学、传播、临床和病理学特征、免疫学、发病机制、分子生物学和疫苗开发。此外，还对最近从人类和其他动物物种中鉴定出的类圆环病毒 DNA 序列及其生物学意义进行了综述。本期特刊中的文章指出了当前 PCV2 研究中的空白，并为未来研究指明了方向。
