Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Germany.
Neurosci Lett. 2012 Jan 24;507(2):161-6. doi: 10.1016/j.neulet.2011.12.014. Epub 2011 Dec 17.
Sleep restriction is a widespread phenomenon, specifically in adolescents. This study investigated the impact of increasing sleep restriction in adolescents on cortisol levels and daytime sleepiness. Eighty-eight healthy adolescents were randomized to five sleep restriction protocols (four consecutive nights with 9, 8, 7, 6, or 5 h time in bed). Polysomnography (baseline and last experimental night) and multiple sleep latency test (day 6) data were obtained. Saliva cortisol levels were assessed half-hourly in the evening before and in the morning after the baseline and the last experimental night. Four nights of sleep restriction in healthy adolescents lead to a linear increase of objective sleepiness, but had no significant effect on evening or morning cortisol levels. The lack of detrimental effects of sleep restriction on cortisol levels might be due to compensation mechanisms during sleep.
睡眠限制是一种普遍存在的现象，特别是在青少年中。本研究旨在探讨增加青少年的睡眠限制对皮质醇水平和日间嗜睡的影响。88 名健康青少年被随机分配到五个睡眠限制方案中（连续四晚的卧床时间分别为 9、8、7、6 或 5 小时）。进行多导睡眠图（基线和最后一个实验夜）和多次睡眠潜伏期测试（第 6 天）。在基线和最后一个实验夜前后的晚上和早上，每隔半小时评估唾液皮质醇水平。在健康青少年中，四晚的睡眠限制导致客观嗜睡呈线性增加，但对傍晚或早晨的皮质醇水平没有显著影响。睡眠限制对皮质醇水平没有不利影响，这可能是由于睡眠期间的补偿机制。
