首次报道动物源屎肠球菌携带耐多药基因 cfr。
First report of the multidrug resistance gene cfr in Enterococcus faecalis of animal origin.
机构信息
Key Laboratory of Development and Evaluation of Chemical and Herbal Drugs for Animal Use, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China.
出版信息
Antimicrob Agents Chemother. 2012 Mar;56(3):1650-4. doi: 10.1128/AAC.06091-11. Epub 2011 Dec 27.
Abstract
The multiresistance gene cfr was identified for the first time in an Enterococcus faecalis isolate of animal origin. The 32,388-bp plasmid pEF-01, which carried the cfr gene, was sequenced completely. Three copies of the insertion sequence IS1216 were identified in pEF-01, and the detection of a cfr- and IS1216-containing amplicon by inverse PCR suggests that IS1216 may play a role in the dissemination of cfr by a recombination process.
摘要
耐多药基因 cfr 最初在一株动物源屎肠球菌分离株中被发现。携带 cfr 基因的 32388bp 质粒 pEF-01 被完全测序。在 pEF-01 中鉴定出三个插入序列 IS1216，反向 PCR 检测到含有 cfr 和 IS1216 的扩增子表明，IS1216 可能通过重组过程在 cfr 的传播中发挥作用。
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