Stewart I, Peel S
Anat Embryol (Berl). 1979 May 3;156(1):103-14. doi: 10.1007/BF00315718.
Rats were subjected to ovariectomy or a control operation on day 10 of pregnancy and light and electron microscope studies carried out to examine the cells of the decidua basalis and the mesometrial triangle. Degeneration of the decidua basalis was rapid but proliferation in the mesometrial triangle and differentiation of the typical granulated cells continued for some time, and resulted in the formation of a metrial gland. The earliest effect noted in the metrial gland was the appearance of inclusions in the fibroblast-like stromal cells one day after ovariectomy. During the next four days many stromal cells became packed with a variety of inclusions and it is suggested that some of these may represent phagocytosed cellular debris. Some debris appeared to be in intercellular spaces and was probably derived from granulated cells. Some granulated cells appeared to develop apparently empty vacuoles and this may be a preliminary stage in degeneration. Although granulated cells decreased to become very few in number five days after ovariectomy, the precise mechanism of their loss and the relationship of this to the hormonal environment could not be established.
在妊娠第10天对大鼠进行卵巢切除术或对照手术，并进行光镜和电镜研究，以检查基底蜕膜和子宫系膜三角区的细胞。基底蜕膜的退化迅速，但子宫系膜三角区的增殖和典型颗粒细胞的分化持续了一段时间，并导致了蜕膜腺的形成。在卵巢切除术后一天，在蜕膜腺中最早观察到的效应是成纤维细胞样基质细胞中出现包涵体。在接下来的四天里，许多基质细胞充满了各种包涵体，有人认为其中一些可能代表吞噬的细胞碎片。一些碎片似乎存在于细胞间隙中，可能来源于颗粒细胞。一些颗粒细胞似乎形成了明显的空泡，这可能是退化的一个初步阶段。尽管颗粒细胞在卵巢切除术后五天减少到数量很少，但它们消失的精确机制以及这与激素环境的关系尚无法确定。
