秀丽隐杆线虫中的激光显微手术。
Laser microsurgery in Caenorhabditis elegans.
作者信息
Fang-Yen Christopher, Gabel Christopher V, Samuel Aravinthan D T, Bargmann Cornelia I, Avery Leon
机构信息
Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
出版信息
Methods Cell Biol. 2012;107:177-206. doi: 10.1016/B978-0-12-394620-1.00006-0.
Abstract
Laser killing of cell nuclei has long been a powerful means of examining the roles of individual cells in C. elegans. Advances in genetics, laser technology, and imaging have further expanded the capabilities and usefulness of laser surgery. Here, we review the implementation and application of currently used methods for target edoptical disruption in C. elegans.
摘要
长期以来，激光杀死细胞核一直是研究秀丽隐杆线虫中单个细胞作用的有力手段。遗传学、激光技术和成像技术的进步进一步扩展了激光手术的能力和用途。在此，我们综述了秀丽隐杆线虫中目前用于靶向光学破坏的方法的实施和应用。
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Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase.钙和环腺苷酸促进秀丽隐杆线虫轴突再生，需要 Dlk-1 激酶。
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