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补骨脂——“库什塔纳希尼”

Psoralea corylifolia Linn.-"Kushtanashini".

作者信息

Khushboo P S, Jadhav V M, Kadam V J, Sathe N S

机构信息

Department of Quality Assurance, Bharati Vidyapeeth's College of Pharmacy, Sector 8, CBD Belapur, Navi-Mumbai - 400 614, India.

出版信息

Pharmacogn Rev. 2010 Jan;4(7):69-76. doi: 10.4103/0973-7847.65331.

DOI:10.4103/0973-7847.65331
PMID:22228944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3249905/
Abstract

Plants have been the basis of many traditional medicines throughout the world for thousands of years and continue to provide new remedies to mankind. Plants have been one of the important sources of medicines since the beginning of human civilization. The recent resurgence of plant remedies resulted from several factors, such as effectiveness of plant medicines and lesser side effects compared with modern medicines. Psoralea corylifolia, commonly known as babchi, is a popular herb, which has since long been used in traditional Ayurvedic and Chinese medicine for its magical effects to cure various skin diseases. This plant is also pharmacologically studied for its chemoprotective, antioxidant, antimicrobial, and antiinflammatory properties. This review attempts to highlight the available literature on P. corylifolia with respect to its ethnobotany, pharmacognostic characteristics, traditional uses, chemical constituents, and summary of its various pharmacologic activities and clinical effects. Other aspects, such as toxicology and precautions are also discussed. This will be helpful to create interest toward babchi and may be useful in developing new formulations with more therapeutic and economical value.

摘要

几千年来,植物一直是世界各地许多传统药物的基础,并继续为人类提供新的治疗方法。自人类文明开始以来,植物一直是药物的重要来源之一。植物疗法最近的复兴源于几个因素,例如植物药物的有效性以及与现代药物相比副作用较小。补骨脂,俗称胡芦巴,是一种广受欢迎的草药,长期以来一直在传统阿育吠陀医学和中医中用于治疗各种皮肤病,因其神奇功效而闻名。对这种植物还进行了药理研究,以了解其化学保护、抗氧化、抗菌和抗炎特性。本综述试图突出关于补骨脂的现有文献,内容涉及民族植物学、生药学特征、传统用途、化学成分以及其各种药理活性和临床效果的总结。还讨论了其他方面,如毒理学和注意事项。这将有助于激发对胡芦巴的兴趣,并可能有助于开发具有更高治疗和经济价值的新制剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/3249905/51089a57b5f8/PRev-4-69-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/3249905/3824b277674b/PRev-4-69-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/3249905/ca01717cdc4a/PRev-4-69-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/3249905/51089a57b5f8/PRev-4-69-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/3249905/3824b277674b/PRev-4-69-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/3249905/ca01717cdc4a/PRev-4-69-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b9b/3249905/51089a57b5f8/PRev-4-69-g003.jpg

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Biol Pharm Bull. 2008 Jun;31(6):1109-14. doi: 10.1248/bpb.31.1109.
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Chemical fingerprint and quantitative analysis of fructus psoraleae by high-performance liquid chromatography.补骨脂的化学指纹图谱及高效液相色谱定量分析
J Sep Sci. 2007 Apr;30(6):813-8. doi: 10.1002/jssc.200600339.
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Studies on the chemical constituents of Psoralea corylifolia L.
Front Pharmacol. 2025 Jan 20;15:1521040. doi: 10.3389/fphar.2024.1521040. eCollection 2024.
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The Influence of Phytoconstituents for the Management of Antipsoriatic Activity in Various Animal Models.植物成分对各种动物模型抗银屑病活性的影响。
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A Rare Cause of Acute on Chronic Liver Failure (ACLF): Bakuchi-Induced Liver Injury.慢性肝衰竭急性发作(ACLF)的罕见病因:补骨脂致肝损伤。
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Preparative isolation and purification of psoralen and isopsoralen from Psoralea corylifolia by high-speed counter-current chromatography.高速逆流色谱法从补骨脂中制备分离和纯化补骨脂素和异补骨脂素
J Chromatogr A. 2004 Nov 19;1057(1-2):225-8. doi: 10.1016/j.chroma.2004.09.049.