Centre for Violence Prevention, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Psychol Med. 2012 Sep;42(9):1977-83. doi: 10.1017/S0033291711003060. Epub 2012 Jan 12.
Associations between child maltreatment and adult violence, often termed the 'cycle of violence', are well documented. However, the nature of such links after appropriate control for confounding remains uncertain. We aimed to determine whether child maltreatment causes adult violent offending or whether suggested links are due to genetic or family environment confounding.
A total of 18 083 20- to 47-year-old twins from the Swedish population-based Study of Twin Adults: Genes and Environment (STAGE) participated. We linked information on self-reported child maltreatment with national register data on convictions for adult crime. We used a case-control design to elucidate associations among unrelated individuals and also conducted within-discordant twin pair analyses to estimate the influence of familial confounding on this association.
The odds ratio (OR), adjusted for age, sex and education, for violent offending in maltreated children grown up versus unrelated controls was 1.98 [95% confidence interval (CI) 1.52-2.57]. However, the association decreased to 1.18 (95% CI 0.62-2.25) when maltreated children were compared to their non-maltreated twins, suggesting substantial confounding by genetic or family environmental factors (within-twin OR<1.98) and a weak, non-significant causal effect (within-twin OR>1.00). Familial confounding was also pronounced for the association between child maltreatment and any offending.
Childhood maltreatment was found to be a weak causal risk factor for adult violent offending; hence, reducing maltreatment might decrease violent crime less than previously expected. Instead, considerable familial confounding of the link between child maltreatment and adult violent offending suggests that prevention strategies need to address overlapping genetic and/or family environmental liability for abusive and violent behavior.
儿童虐待与成人暴力之间的关联,通常被称为“暴力循环”,已有充分的文献记载。然而,在适当控制混杂因素后,这种关联的性质仍不确定。我们旨在确定儿童虐待是否导致成人暴力犯罪,或者所提出的关联是否是由于遗传或家庭环境混杂因素造成的。
共有来自瑞典基于人群的成年双胞胎研究:基因与环境(STAGE)的 18083 名 20 至 47 岁的双胞胎参与了此项研究。我们将自我报告的儿童虐待信息与成人犯罪定罪的国家登记数据进行了关联。我们使用病例对照设计来阐明无关联个体之间的关联,并且还进行了不一致双胞胎对分析,以估计家庭混杂因素对这种关联的影响。
调整年龄、性别和教育因素后,与无关联对照组相比,在受虐待的儿童中,暴力犯罪的比值比(OR)为 1.98(95%置信区间 [CI] 1.52-2.57)。然而,当将受虐待的儿童与未受虐待的双胞胎进行比较时,该关联下降至 1.18(95% CI 0.62-2.25),表明遗传或家庭环境因素存在大量混杂(双胞胎内 OR<1.98),并且因果效应较弱且无统计学意义(双胞胎内 OR>1.00)。儿童虐待与任何犯罪之间的关联也存在明显的家族混杂。
研究发现,儿童期虐待是成人暴力犯罪的一个较弱的因果风险因素;因此,减少虐待可能不会像以前预期的那样减少暴力犯罪。相反,儿童虐待与成人暴力犯罪之间关联的强烈家族混杂表明,预防策略需要解决虐待和暴力行为的重叠遗传和/或家庭环境易感性。