Gynecology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
Hematol Oncol Clin North Am. 2012 Feb;26(1):169-94. doi: 10.1016/j.hoc.2011.11.001. Epub 2011 Dec 16.
Regardless of cancer origin or age of onset, the disease and its treatment can produce short- and long-term sequelae (ie, sexual dysfunction, infertility, or lymphedema) that adversely affect quality of life (QOL). This article outlines the primary contemporary issues or concerns that may affect QOL and offers strategies to offset or mitigate QOL disruption. These contemporary issues are identified within the domains of sexual functioning, reproductive issues, lymphedema, and the contribution of health-related QOL in influential gynecologic cancer clinical trials.
无论癌症的起源或发病年龄如何,疾病及其治疗都会产生短期和长期的后遗症(即性功能障碍、不孕或淋巴水肿),从而对生活质量(QOL)产生不利影响。本文概述了可能影响 QOL 的主要当代问题或关注点,并提供了抵消或减轻 QOL 破坏的策略。这些当代问题在性功能、生殖问题、淋巴水肿以及健康相关 QOL 在有影响力的妇科癌症临床试验中的作用等领域得到了确定。