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影响文心兰叶绿体基因组同义密码子使用偏性的因素。

Factors affecting synonymous codon usage bias in chloroplast genome of oncidium gower ramsey.

机构信息

School of Biochemical and Environmental Engineering, Nanjing Xiaozhuang University, Nanjing 211171, Jiangsu, China.

出版信息

Evol Bioinform Online. 2011;7:271-8. doi: 10.4137/EBO.S8092. Epub 2011 Nov 14.

DOI:10.4137/EBO.S8092
PMID:22253533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3255522/
Abstract

Oncidium Gower Ramsey is a fascinating and important ornamental flower in floral industry. In this research, the complete nucleotide sequence of the chloroplast genome in Oncidium Gower Ramsey was studied, then analyzed using Codonw software. Correspondence analysis and method of effective number of codon as Nc-plot were conducted to analyze synonymous codon usage. According to the corresponding analysis, codon bias in the chloroplast genome of Oncidium Gower Ramsey is related to their gene length, mutation bias, gene hydropathy level of each protein, gene function and selection or gene expression only subtly affect codon usage. This study will provide insights into the molecular evolution study and high-level transgene expression.

摘要

文心兰是花卉产业中一种极具魅力和重要的观赏花卉。本研究对文心兰叶绿体基因组全序列进行了研究,然后使用 Codonw 软件进行了分析。通过对应分析和有效密码子数方法(Nc-plot)分析同义密码子的使用情况。根据对应分析,文心兰叶绿体基因组密码子偏好性与基因长度、突变偏好性、每个蛋白质的基因亲水性水平、基因功能以及选择或基因表达有关,仅对密码子的使用产生细微影响。本研究将为分子进化研究和高水平转基因表达提供新的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/3255522/f1263568b861/ebo-7-2011-271f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/3255522/0a8a11fa00ee/ebo-7-2011-271f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/3255522/f1263568b861/ebo-7-2011-271f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/3255522/0a8a11fa00ee/ebo-7-2011-271f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b35b/3255522/f1263568b861/ebo-7-2011-271f2.jpg

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