Hahn L J, Kloiber R, Leininger R W, Vimy M J, Lorscheider F L
Department of Radiology, University of Calgary, Faculty of Medicine, Alberta, Canada.
FASEB J. 1990 Nov;4(14):3256-60. doi: 10.1096/fasebj.4.14.2227216.
The fate of mercury (Hg) released from dental "silver" amalgam tooth fillings into human mouth air is uncertain. A previous report about sheep revealed uptake routes and distribution of amalgam Hg among body tissues. The present investigation demonstrates the bodily distribution of amalgam Hg in a monkey whose dentition, diet, feeding regimen, and chewing pattern closely resemble those of humans. When amalgam fillings, which normally contain 50% Hg, are made with a tracer of radioactive 203Hg and then placed into monkey teeth, the isotope appears in high concentration in various organs and tissues within 4 wk. Whole-body images of the monkey revealed that the highest levels of Hg were located in the kidney, gastrointestinal tract, and jaw. The dental profession's advocacy of silver amalgam as a stable tooth restorative material is not supported by these findings.
从牙科“银”汞合金补牙材料释放到人体口腔空气中的汞（Hg）的最终去向尚不确定。之前一份关于绵羊的报告揭示了汞合金汞在身体组织中的摄取途径和分布情况。本研究展示了汞合金汞在一只猴子体内的分布情况，这只猴子的牙列、饮食、喂养方式和咀嚼模式与人类极为相似。当用放射性203Hg示踪剂制作通常含有50%汞的汞合金补牙材料，然后植入猴子牙齿后，该同位素在4周内会在各种器官和组织中以高浓度出现。对这只猴子的全身成像显示，汞含量最高的部位是肾脏、胃肠道和颌部。这些研究结果并不支持牙科行业对银汞合金作为一种稳定牙齿修复材料的推崇。
