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化脓性肉芽肿:20 例患者应用 1064nm 长脉冲掺钕钇铝石榴石激光治疗。

Pyogenic granuloma: treatment with the 1,064-nm long-pulsed neodymium-doped yttrium aluminum garnet laser in 20 patients.

机构信息

Laserklinik Karlsruhe, Karlsruhe, Germany.

出版信息

Dermatol Surg. 2012 Jun;38(6):918-23. doi: 10.1111/j.1524-4725.2012.02344.x. Epub 2012 Jan 24.

Abstract

BACKGROUND

There are various therapeutic options for the treatment of pyogenic granuloma (PyG), but the results are frequently unsatisfactory, especially at difficult sites and with extensive lesions.

OBJECTIVE

To evaluate the success of treatment of PyG using the 1,064-nm neodymium-doped yttrium aluminum garnet (Nd:YAG) laser and to compare it with state-of-the-art treatment methods.

MATERIALS AND METHODS

Twenty patients with PyG were treated using the long-pulsed 1,064-nm Nd:YAG laser with fluences of 60 to 180 J/cm(2) , a spot size of 7 mm, and a pulse duration of 40 ms. One to four treatment sessions were necessary for complete removal.

RESULTS

Recurrence-free healing occurred in 19 of 20 patients (follow-up ≥ 6 months, maximum 22 months). Because of heavy bleeding, one nonresponder was successfully treated using a carbon dioxide laser. The cosmetic results were good; textural changes of the skin were slight, if present at all.

CONCLUSION

When used with the right strategy and patient cohort, the long-pulse 1,064-nm Nd:YAG laser is an effective, low-risk, minimally invasive method of treating PyG. This type of laser is a good therapeutic option that achieves good cosmetic results, particularly in PyG with a large diameter that are not suitable for treatment using the pulsed dye laser.

摘要

背景

对于化脓性肉芽肿(PyG)的治疗有多种治疗选择,但结果常常不尽如人意,尤其是在困难部位和广泛病变时。

目的

评估 1064nm 掺钕钇铝石榴石(Nd:YAG)激光治疗 PyG 的成功率,并将其与最新治疗方法进行比较。

材料和方法

20 例 PyG 患者采用长脉冲 1064nm Nd:YAG 激光治疗,能量密度为 60-180J/cm²,光斑大小为 7mm,脉宽为 40ms。需要 1-4 次治疗才能完全清除。

结果

20 例患者中有 19 例(随访≥6 个月,最长 22 个月)无复发愈合。由于大量出血,1 例无反应者成功接受二氧化碳激光治疗。美容效果良好;皮肤质地变化轻微,如果有的话。

结论

当与正确的策略和患者群体一起使用时,长脉冲 1064nm Nd:YAG 激光是一种有效、低风险、微创的治疗 PyG 的方法。这种类型的激光是一种很好的治疗选择,可获得良好的美容效果,特别是对于直径较大、不适合脉冲染料激光治疗的 PyG。

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