Franklyn K M, Warmington J R, Ott A K, Ashman R B
Department of Medical Technology, Curtin University of Technology, Bentley, WA 6102.
Immunol Cell Biol. 1990 Jun;68 ( Pt 3):173-8. doi: 10.1038/icb.1990.24.
Antibody to an immunodominant antigen of approximately 48 kDa is found in a high proportion of patients with mucocutaneous or systemic infections of the yeast Candida albicans. A cDNA encoding part of the 48 kDa antigen has been isolated. From the deduced amino acid sequence of the cDNA clone, the 48 kDa antigen shows homology to the enzyme enolase.
在患有白色念珠菌黏膜皮肤或全身感染的患者中,很大一部分人发现了针对一种约48 kDa免疫显性抗原的抗体。已分离出编码该48 kDa抗原部分序列的cDNA。根据该cDNA克隆推导的氨基酸序列,该48 kDa抗原与烯醇化酶具有同源性。