Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Kasumigaseki, Chiyoda-ku, Tokyo, Japan.
Epidemiol Infect. 2012 Nov;140(11):2074-81. doi: 10.1017/S0950268812000039. Epub 2012 Jan 27.
This study determined the prevalence and antimicrobial susceptibility of Salmonella isolated from broiler flocks in Japan. Caecal dropping samples were collected from 288 broiler flocks between November 2007 and February 2010. Salmonella was prevalent in 248 (86·1%) broiler flocks. The top three serovars were S. Infantis, S. Manhattan and S. Schwarzengrund. S. Infantis was found in all regions tested in this study. However, S. Manhattan and S. Schwarzengrund were frequently found only in the western part of Japan. High antimicrobial resistance rates were observed against oxytetracycline (90·2%), dihydrostreptomycin (86·7%) and ampicillin (36·5%), and 258 (90·5%) of 285 isolates were resistant to two or more antimicrobial agents. Interestingly, 26·3% of isolates were resistant to ceftiofur, especially 38·1% of S. Infantis isolates, although its use in broilers has not been approved in Japan. This study showed that Salmonella is highly prevalent (86·1%) in Japanese broiler flocks, that 90·5% of Salmonella isolates were multidrug-resistant, and that S. Infantis frequently exhibited resistance to cephalosporin antimicrobial agents.
本研究旨在确定日本肉鸡养殖场中分离出的沙门氏菌的流行情况和药敏谱。于 2007 年 11 月至 2010 年 2 月期间，采集了 288 个肉鸡养殖场的盲肠粪便样本。结果显示，248 个（86.1%）肉鸡养殖场中存在沙门氏菌。排名前三的血清型分别为肠炎沙门氏菌、曼哈顿沙门氏菌和施氏沙门氏菌。本研究检测的所有地区均存在肠炎沙门氏菌，但曼哈顿沙门氏菌和施氏沙门氏菌仅在日本西部频繁检出。对土霉素（90.2%）、二氢链霉素（86.7%）和氨苄西林（36.5%）的耐药率较高，285 株分离株中有 258 株（90.5%）对两种或两种以上抗菌药物耐药。有趣的是，26.3%的分离株对头孢噻呋耐药，尤其是肠炎沙门氏菌分离株的耐药率为 38.1%，尽管头孢噻呋在日本尚未被批准用于肉鸡。本研究表明，沙门氏菌在日本肉鸡养殖场中高度流行（86.1%），90.5%的沙门氏菌分离株为多重耐药株，肠炎沙门氏菌对头孢菌素类抗菌药物经常表现出耐药性。
