Agrawal S S, Ray R S
Department of Pharmacology, Delhi Institute of Pharmaceutical sciences and Research (DIPSAR), University of Delhi, Pushp Vihar, Sector 3, M.B. Road, New Delhi 110017, India.
J Toxicol. 2012;2012:237506. doi: 10.1155/2012/237506. Epub 2012 Jan 12.
The use of tobacco products as dentifrices is still prevalent in various parts of India. Tobacco use in dentifrices is a terrible scourge which motivates continued use despite its harmful effects. Indian legislation prohibits the use of nicotine in dentifrices. Nicotine is primarily injurious to people because it is responsible for tobacco addiction and is dependence forming. The present study was motivated by an interest in examining the presence of nicotine in these dentifrices. Our earlier report indicates the presence of nicotine in toothpowders. To further curb the menace of tobacco, our team again analysed the toothpowder brands of previous years and in toothpastes as well. Eight brands of commonly used toothpastes and toothpowders were evaluated by gas chromatography-mass spectroscopy. On the whole, there are a few successes but much remains to be done. Our findings indicated the presence of nicotine in two brands of dant manjans and four brands of toothpastes. Further our finding underscores the need for stringent regulations by the regulatory authorities for preventing the addition of nicotine in these dentifrices. Hence government policy needs to be targeted towards an effective control of tobacco in these dentifrices and should be properly addressed.
在印度各地,将烟草制品用作牙膏仍然很普遍。牙膏中使用烟草是一种可怕的祸害,尽管有有害影响,但仍促使人们持续使用。印度法律禁止在牙膏中使用尼古丁。尼古丁主要对人有害,因为它会导致烟草成瘾并形成依赖。本研究的动机是考察这些牙膏中尼古丁的存在情况。我们之前的报告表明牙粉中存在尼古丁。为了进一步遏制烟草的威胁,我们的团队再次分析了前几年的牙粉品牌以及牙膏。通过气相色谱 - 质谱联用仪对八个常用牙膏和牙粉品牌进行了评估。总体而言,有一些成效,但仍有许多工作要做。我们的研究结果表明,两种品牌的丹特曼占(一种印度传统牙齿清洁用品)和四种品牌的牙膏中存在尼古丁。此外,我们的研究结果强调监管当局需要制定严格的法规,以防止在这些牙膏中添加尼古丁。因此,政府政策需要针对有效控制这些牙膏中的烟草问题,并应妥善解决。