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基于杂化铱配合物的强双光子诱导磷光高尔基体特异性体外标记物。

A strong two-photon induced phosphorescent Golgi-specific in vitro marker based on a heteroleptic iridium complex.

机构信息

Department of Chemistry and Institute of Advanced Materials, Hong Kong Baptist University, Kowloon Tong, Hong Kong, PR China.

出版信息

Chem Commun (Camb). 2012 Mar 4;48(19):2525-7. doi: 10.1039/c2cc16993b. Epub 2012 Jan 30.

DOI:10.1039/c2cc16993b
PMID:22288076
Abstract

A new heteroleptic iridium complex demonstrated low cytotoxicity and near-infrared excitation (via two-photon absorption) for target-specific in vitro Golgi imaging in various cell lines (HeLa and A549 cells) with two-photon absorption cross section (~350 GM) in DMSO.

摘要

一种新的杂化铱配合物表现出低细胞毒性和近红外激发（通过双光子吸收），在各种细胞系（HeLa 和 A549 细胞）中具有双光子吸收截面（~350 GM），可用于靶向特异性高尔基体内成像。

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