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从水竹叶叶提取物中分离得到的苯甲酸和苯乙醇类衍生物的抗菌潜力。

Antibacterial potential of benzoate and phenylethanoid derivatives isolated from Acanthus ilicifolius L. leaf extracts.

机构信息

School of Marine Sciences, Department of Oceanography and Coastal Area Studies, Alagappa University, Thondi Campus, Thondi 623409, Ramanathapuram District, Tamil Nadu, India.

出版信息

Nat Prod Res. 2012;26(23):2270-3. doi: 10.1080/14786419.2011.652962. Epub 2012 Jan 31.

DOI:10.1080/14786419.2011.652962
PMID:22292885
Abstract

The antibacterial activities of column chromatography fractions of n-hexane, benzene, chloroform, acetone, ethanol and water extracts from Acanthus ilicifolius were tested against 24 bacterial pathogens. The antibacterial activity was performed using agar diffusion method. Most active fractions were further investigated through UV-Vis, (13)C, (1)H-NMR, FT-IR for the structural elucidation. The antibacterial activity of the extracts was identified as 6-hydroxy-benzoxazolinone, (Z)-4-coumaric acid 4-O-β-D-glucopyranoside and 3,5-dimethoxy-4-hydroxy methyl benzoate.

摘要

采用琼脂扩散法测试了老鼠簕叶的正己烷、苯、氯仿、丙酮、乙醇和水提取物的柱层析部分对 24 种细菌病原体的抗菌活性。通过 UV-Vis、(13)C、(1)H-NMR、FT-IR 对具有活性的部分进行了结构鉴定,确定提取物的抗菌活性成分为 6-羟基苯并恶唑啉酮、(Z)-4-肉桂酸 4-O-β-D-吡喃葡萄糖苷和 3,5-二甲氧基-4-羟甲基苯甲酸酯。

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