Genomics Division, Lawrence Berkeley National Laboratory, 1 Cycltotron Road MS 64-121, Berkeley, CA 94720, USA.
Genome Biol. 2012 Jan 31;13(1):R5. doi: 10.1186/gb-2012-13-1-r5.
We present Uberon, an integrated cross-species ontology consisting of over 6,500 classes representing a variety of anatomical entities, organized according to traditional anatomical classification criteria. The ontology represents structures in a species-neutral way and includes extensive associations to existing species-centric anatomical ontologies, allowing integration of model organism and human data. Uberon provides a necessary bridge between anatomical structures in different taxa for cross-species inference. It uses novel methods for representing taxonomic variation, and has proved to be essential for translational phenotype analyses. Uberon is available at http://uberon.org.
我们呈现了 Uberon，这是一个集成的跨物种本体，由超过 6500 个类组成，代表了各种解剖实体，根据传统的解剖分类标准进行组织。该本体以物种中立的方式表示结构，并包含与现有以物种为中心的解剖本体的广泛关联，允许整合模式生物和人类数据。Uberon 为不同分类群中的解剖结构之间提供了跨物种推断的必要桥梁。它使用了新的方法来表示分类学上的变化，并且已经被证明对于转化表型分析是必不可少的。Uberon 可在 http://uberon.org 上获得。
