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对处于存活临界状态的新生儿复苏时进行胸外按压和使用肾上腺素:是、否还是不确定?

Chest compressions and epinephrine during resuscitation of infants born at the border of viability: Yes, no or maybe?

作者信息

Moore Gregory P, Daboval Thierry, Coughlin Kevin W

机构信息

Department of Pediatrics, Division of Neonatology, Children's Hospital of Eastern Ontario;

出版信息

Paediatr Child Health. 2011 Feb;16(2):87-90. doi: 10.1093/pch/16.2.87.

DOI:10.1093/pch/16.2.87
PMID:22294868
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3043040/
Abstract

Neonatology, in large part due to its population of babies born at the edge of viability, is rife with bioethical issues. This unique population is at high risk of mortality and considerable neurodevelopmental morbidity. One contentious, ongoing debate concerns whether these extremely low birth weight infants born at the border of viability should, if required by the Neonatal Resuscitation Program guidelines, receive chest compressions and epinephrine as part of their delivery room resuscitation. The present article, through a case presentation and discussion based on the ethical framework of principlism, provides readers with a thoughtful approach to the controversial issue of the provision of chest compressions and epinephrine as part of resuscitation for extremely low birth weight infants born at the border of viability.

摘要

新生儿学,很大程度上由于其收治的是处于生存边缘出生的婴儿,充满了生物伦理问题。这一独特群体面临着高死亡率和相当高的神经发育疾病风险。一场持续存在的有争议的辩论涉及,对于这些在生存边缘出生的极低出生体重婴儿,如果根据新生儿复苏计划指南有需要,在产房复苏时是否应接受胸外按压和肾上腺素治疗。本文通过一个病例介绍,并基于原则主义的伦理框架进行讨论,为读者提供一种对有争议问题的深入思考方法,即对于在生存边缘出生的极低出生体重婴儿,在复苏时提供胸外按压和肾上腺素治疗的问题。

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Outcomes at age 2 years of infants < 28 weeks' gestational age born in Victoria in 2005.2005 年在维多利亚州出生的胎龄<28 周的婴儿在 2 岁时的结局。
J Pediatr. 2010 Jan;156(1):49-53.e1. doi: 10.1016/j.jpeds.2009.07.013.
2
Moral reflections on neonatal intensive care.关于新生儿重症监护的伦理思考
Pediatrics. 2009 Feb;123(2):595-7. doi: 10.1542/peds.2008-1648.
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What information do parents want from the antenatal consultation?父母希望从产前咨询中获得哪些信息?
Paediatr Child Health. 2007 Mar;12(3):191-6. doi: 10.1093/pch/12.3.191.
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Reducing lung injury during neonatal resuscitation of preterm infants.减少早产儿新生儿复苏期间的肺损伤。
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Complications associated with neonatal resuscitation.
Resuscitation. 2009 Jan;80(1):4-5. doi: 10.1016/j.resuscitation.2008.09.007. Epub 2008 Oct 31.
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Effect of chest compressions only during experimental basic life support on alveolar collapse and recruitment.实验性基础生命支持期间仅进行胸外按压对肺泡塌陷和复张的影响。
Resuscitation. 2008 Oct;79(1):125-32. doi: 10.1016/j.resuscitation.2008.03.228. Epub 2008 Jun 16.
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Neonatology. 2008;93(4):295-301. doi: 10.1159/000121455. Epub 2008 Jun 5.
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The role of resuscitation drugs and placental transfusion in the delivery room management of newborn infants.复苏药物及胎盘输血在新生儿产房管理中的作用。
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