巴西一家三级护理医院中肉毒杆菌毒素注射前颈部肌张力障碍患者的生活质量。
Quality of life in individuals with cervical dystonia before botulinum toxin injection in a Brazilian tertiary care hospital.
作者信息
Queiroz Mariana Ribeiro, Chien Hsin Fen, Barbosa Egberto Reis
机构信息
Movement Disorders Clinic of the Division of Neurology, Hospital das Clínicas, University of São Paulo, School of Medicine, Brazil.
出版信息
Arq Neuropsiquiatr. 2011 Dec;69(6):900-4. doi: 10.1590/s0004-282x2011000700010.
OBJECTIVE
The purpose of this study was to evaluate quality of life (QoL) in a Brazilian population of individuals with cervical dystonia (CD) without effect of botulinum toxin (BTx) or with only residual effect of BTx, and identify possible physical and social aspects that affect their QoL.
METHOD
Sixty five out of sixty seven consecutive patients with CD were assessed with two instruments: Short-form Health Survey with 36 questions (SF-36) and Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS).
RESULTS
Severity of CD (TWSTRS) correlated moderately with two SF-36 subscale: role-physical (r= -0.42) and body pain (r= -0.43). Women also scored worse in two subscale of SF-36: vitality (p<0.05) and mental-health (p<0.005).
CONCLUSION
Severity of CD and gender (female) were the main factors related to a worse QoL perception. These findings may help health professionals to predict which characteristics could lead to worse QoL, and therefore, better target their interventions to lessen the burden caused by CD.
目的
本研究旨在评估巴西未使用肉毒杆菌毒素（BTx）或仅存在BTx残余效应的痉挛性斜颈（CD）患者群体的生活质量（QoL），并确定可能影响其生活质量的身体和社会因素。
方法
连续67例CD患者中的65例接受了两种评估工具的评估：36个问题的简短健康调查问卷（SF-36）和多伦多西部痉挛性斜颈评定量表（TWSTRS）。
结果
CD严重程度（TWSTRS）与SF-36的两个子量表呈中度相关：生理功能（r = -0.42）和身体疼痛（r = -0.43）。女性在SF-36的两个子量表上得分也较低：活力（p<0.05）和心理健康（p<0.005）。
结论
CD严重程度和性别（女性）是与较差生活质量感知相关的主要因素。这些发现可能有助于卫生专业人员预测哪些特征可能导致较差的生活质量，从而更好地针对干预措施，减轻CD造成的负担。
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