Comella Cynthia L, Perlmutter Joel S, Jinnah Hyder A, Waliczek Tracy A, Rosen Ami R, Galpern Wendy R, Adler Charles A, Barbano Richard L, Factor Stewart A, Goetz Christopher G, Jankovic Joseph, Reich Stephen G, Rodriguez Ramon L, Severt William L, Zurowski Mateusz, Fox Susan H, Stebbins Glenn T
Rush University Medical Center, Chicago, Illinois, USA.
Washington University School of Medicine, St. Louis, Missouri, USA.
Mov Disord. 2016 Apr;31(4):563-9. doi: 10.1002/mds.26534. Epub 2016 Mar 12.
The aim of this study was to test the clinimetric properties of the Comprehensive Cervical Dystonia Rating Scale. This is a modular scale with modifications of the Toronto Western Spasmodic Torticollis Rating Scale (composed of three subscales assessing motor severity, disability, and pain) now referred to as the revised Toronto Western Spasmodic Torticollis Scale-2; a newly developed psychiatric screening instrument; and the Cervical Dystonia Impact Profile-58 as a quality of life measure.
Ten dystonia experts rated subjects with cervical dystonia using the comprehensive scale. Clinimetric techniques assessed each module of the scale for reliability, item correlation, and factor structure.
There were 208 cervical dystonia patients (73% women; age, 59 ± 10 years; duration, 15 ± 12 years). Internal consistency of the motor severity subscale was acceptable (Cronbach's alpha = 0.57). Item to total correlations showed that elimination of items with low correlations (<0.20) increased alpha to 0.71. Internal consistency estimates for the subscales for disability and pain were 0.88 and 0.95, respectively. The psychiatric screening scale had a Cronbach's alpha of 0.84 and satisfactory item to total correlations. When the subscales of the Toronto Western Spasmodic Torticollis Scale-2 were combined with the psychiatric screening scale, Cronbach's alpha was 0.88, and construct validity assessment demonstrated four rational factors: motor; disability; pain; and psychiatric disorders. The Cervical Dystonia Impact Profile-58 had an alpha of 0.98 and its construction was validated through a confirmatory factor analysis.
The modules of the Comprehensive Cervical Dystonia Rating Scale are internally consistent with a logical factor structure.
本研究旨在测试综合颈部肌张力障碍评定量表的临床测量特性。这是一个模块化量表,对多伦多西部痉挛性斜颈评定量表进行了修改(由评估运动严重程度、残疾和疼痛的三个子量表组成),现称为修订的多伦多西部痉挛性斜颈量表-2;一个新开发的精神科筛查工具;以及作为生活质量衡量指标的颈部肌张力障碍影响量表-58。
10位肌张力障碍专家使用综合量表对颈部肌张力障碍患者进行评分。临床测量技术评估了量表的每个模块的信度、项目相关性和因子结构。
共有208例颈部肌张力障碍患者(73%为女性;年龄59±10岁;病程15±12年)。运动严重程度子量表的内部一致性尚可(克朗巴哈系数α=0.57)。项目与总分的相关性表明,剔除相关性较低(<0.20)的项目后,α系数增至0.71。残疾和疼痛子量表的内部一致性估计值分别为0.88和0.95。精神科筛查量表的克朗巴哈系数α为0.84,项目与总分的相关性良好。当将多伦多西部痉挛性斜颈量表-2的子量表与精神科筛查量表相结合时,克朗巴哈系数α为0.88,结构效度评估显示有四个合理的因子:运动;残疾;疼痛;以及精神障碍。颈部肌张力障碍影响量表-58的α系数为0.98,其结构通过验证性因子分析得到验证。
综合颈部肌张力障碍评定量表的各个模块内部一致,具有合理的因子结构。