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[食管上括约肌的高分辨率测压法]

[High-resolution manometry of the upper esophageal sphincter].

作者信息

Meyer S, Jungheim M, Ptok M

机构信息

Klinik und Poliklinik für Phoniatrie und Pädaudiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

出版信息

HNO. 2012 Apr;60(4):318-26. doi: 10.1007/s00106-011-2418-5.

Abstract

BACKGROUND

High-resolution manometry (HRM) represents a valuable tool for the evaluation of peristalsis in the oesophagus. Due to the wide spacing of the pressure transducers, however, examination of the upper oesophageal sphincter's relaxation period has not proved satisfactory as yet.

DESIGN

A feasibility study was carried out to clarify whether evaluation of the upper oesophageal sphincter's behaviour during swallows is possible using a catheter with very closely spaced pressure transducers.

SETTING

University hospital.

PROCEDURE

Healthy subjects were analysed using a specially developed catheter as well as a modified software to evaluate whether swallow-associated behaviour could be verified.

RESULTS

Interpreting pressure profiles in terms of resting pressure, residual pressure, relaxation time and maximum peristaltic pressure proved to be feasible. The present analysis supports the existence of distinct dynamic swallow-associated phases, which conform to the phases that had previously been postulated. An additional initial phase, however, should be added.

CONCLUSION

This newly created catheter design in combination with the modified software enable a very detailed evaluation of the sphincter's swallow-associated behaviour and represent a valuable, minimally invasive tool with no exposure to radiation for dysphagia diagnosis as well as treatment planning.

摘要

背景

高分辨率测压法(HRM)是评估食管蠕动的一项重要工具。然而,由于压力传感器间距较大,对上食管括约肌松弛期的检查至今仍不尽人意。

设计

开展一项可行性研究,以明确使用压力传感器间距非常小的导管评估吞咽过程中上食管括约肌行为是否可行。

地点

大学医院。

过程

使用专门研发的导管及改良软件对健康受试者进行分析,以评估是否能够验证与吞咽相关的行为。

结果

从静息压力、残余压力、松弛时间和最大蠕动压力方面解读压力曲线被证明是可行的。目前的分析支持存在明显的与吞咽相关的动态阶段,这与之前假设的阶段相符。不过,应增加一个额外的初始阶段。

结论

这种新设计的导管与改良软件相结合,能够非常详细地评估括约肌与吞咽相关的行为,是一种有价值的微创工具,在吞咽困难诊断及治疗规划中无需暴露于辐射。

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