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头颈部癌症患者的抑郁、疲劳和健康相关生活质量:一项前瞻性试点研究。

Depression, fatigue, and health-related quality of life in head and neck cancer patients: a prospective pilot study.

机构信息

College of Nursing, University of Sao Paulo, Av. Bandeirantes 3900, Monte Alegre, CEP 14040902 Ribeirão Preto, SP, Brazil.

出版信息

Support Care Cancer. 2012 Nov;20(11):2705-11. doi: 10.1007/s00520-012-1390-2.

DOI:10.1007/s00520-012-1390-2
PMID:22302083
Abstract

PURPOSE

To assess the prevalence of depression and fatigue symptoms in head and neck cancer patients during radiotherapy treatment and relate them symptoms with these patients' quality of life.

METHOD

This is a prospective study. The Beck Depression Inventory (BDI), Piper Fatigue Scale-revised and Functional Assessment Cancer Therapy Head and Neck (FACT-H&N) were applied to 41 head and neck cancer patients at three times: at the start of treatment (T1), approximately 15 days after the start of treatment (T2) and at the end of treatment (T3), approximately 30 days after the start of the radiotherapy.

RESULTS

The mean BDI and PIPER increased during the radiotherapy treatment. BDI scores did not demonstrate the presence of depression, although the number of symptoms increased, and the presence of fatigue rose as treatment advanced. The mean FACT H&N decreased in the middle and at the end of treatment, indicating worsening in these patients' Quality of Life.

CONCLUSIONS

Depression and fatigue symptoms increased during radiotherapy treatment, while QoL levels decreased. This demonstrates that these symptoms are strongly correlated and that their presence negatively influenced QoL. At the start of treatment, nurses need to advise patients and plan care, offering interventions to decrease these symptoms and improve QoL.

摘要

目的

评估头颈部癌症患者在放射治疗过程中抑郁和疲劳症状的发生率,并将这些症状与患者的生活质量联系起来。

方法

这是一项前瞻性研究。在三个时间点(治疗开始时(T1)、治疗开始后约 15 天(T2)和治疗结束时(T3)),分别使用贝克抑郁量表(BDI)、改良皮哌尔疲劳量表和癌症治疗功能评估头颈部量表(FACT-H&N)对 41 名头颈部癌症患者进行评估。

结果

放射治疗过程中,BDI 和 PIPER 的平均值增加。BDI 评分未显示存在抑郁,但随着治疗的进行,症状的数量增加,疲劳的出现也增加。在治疗的中期和结束时,FACT-H&N 的平均值下降,表明这些患者的生活质量恶化。

结论

放射治疗过程中抑郁和疲劳症状增加,而生活质量水平下降。这表明这些症状密切相关,其存在对生活质量有负面影响。在治疗开始时,护士需要告知患者并计划护理,提供干预措施以减轻这些症状并提高生活质量。

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