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ABO血型与胰腺癌

ABO blood groups and cancer of the pancreas.

作者信息

Annese V, Minervini M, Gabbrielli A, Gambassi G, Manna R

机构信息

Department of Gastroenterology, C.S.S. Hospital, San Giovanni Rotondo (FG), Italy.

出版信息

Int J Pancreatol. 1990 Mar;6(2):81-8. doi: 10.1007/BF02933042.

DOI:10.1007/BF02933042
PMID:2230362
Abstract

Few investigations discussing an association between ABO blood groups and pancreatic cancer exist. We have selected a series of 224 patients with histologically-confirmed pancreatic cancer, and their ABO blood groups distribution was compared with two control groups: 7086 patients with various diseases (Group 1) and 7320 voluntary blood donors (Group 2). There was an increased number of pancreatic cancer among the patients with blood group B (relative risk 1.5 vs Group 1 p = 0.021; 1.7 vs Group 2 p = 0.0025) and a decreased number in patients with blood group O, when compared with the two control groups.

摘要

很少有研究探讨ABO血型与胰腺癌之间的关联。我们选取了224例经组织学确诊的胰腺癌患者,并将他们的ABO血型分布与两个对照组进行比较:7086例患有各种疾病的患者(第一组)和7320例自愿献血者(第二组)。与两个对照组相比,B血型患者中胰腺癌的数量增加(相对风险为1.5,与第一组相比p = 0.021;1.7,与第二组相比p = 0.0025),而O血型患者中的数量减少。

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本文引用的文献

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ABO Blood Group and the Risk of Pancreatic Neoplasms in Chinese Han Population: A Study at Shanghai Pancreatic Cancer Institute.
ABO血型与中国汉族人群胰腺肿瘤风险:上海胰腺癌研究所的一项研究
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Cancer Med. 2017 Jul;6(7):1531-1540. doi: 10.1002/cam4.1097. Epub 2017 May 29.
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Blood Transfus. 2013 Oct;11(4):491-9. doi: 10.2450/2013.0152-13. Epub 2013 Oct 3.
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The epidemiologic approach to studies of association between HLA and disease. II. Estimation of absolute risks, etiologic and preventive fraction.人类白细胞抗原(HLA)与疾病关联研究的流行病学方法。II. 绝对风险、病因分数及预防分数的估计
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Lewis blood-type may affect the incidence of gastrointestinal cancer.
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