酿酒酵母中一对重复的核糖体蛋白基因连锁对的功能分析。
Functional analysis of a duplicated linked pair of ribosomal protein genes in Saccharomyces cerevisiae.
作者信息
Donovan D M, Remington M P, Stewart D A, Crouse J C, Miles D J, Pearson N J
机构信息
Department of Biological Sciences, University of Maryland, Catonsville 21228.
出版信息
Mol Cell Biol. 1990 Nov;10(11):6097-100. doi: 10.1128/mcb.10.11.6097-6100.1990.
Abstract
Ribosomal protein genes RP28 and S16A (RP55) are closely linked. Another set of this pair of genes exists in the genome (copy 2), genetically unlinked to copy 1. By using gene replacement techniques, we have shown that RP28 from copy 1 is required for vegetative growth and that the cells need S16A from copy 2 to achieve maximum growth rate.
摘要
核糖体蛋白基因RP28和S16A（RP55）紧密连锁。这对基因的另一组存在于基因组中（拷贝2），与拷贝1在遗传上不连锁。通过使用基因置换技术，我们已经表明，拷贝1中的RP28是营养生长所必需的，并且细胞需要拷贝2中的S16A来实现最大生长速率。
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