Can Fam Physician. 2012 Feb;58(2):163-4.
Some of my pregnant patients are afraid to take their antiepileptic drugs during pregnancy because of the known risk of malformations and the neurodevelopmental problems associated with valproic acid. Are there similar concerns with carbamazepine?
Similar to valproic acid, carbamazepine increases the risk of neural tube defects; however, it does not increase the risk of other malformations. Carbamazepine is also not associated with an increased risk of developmental delay.
我的一些孕妇患者因为已知的畸形风险以及与丙戊酸相关的神经发育问题而害怕在怀孕期间服用抗癫痫药物。卡马西平是否存在类似的担忧?
与丙戊酸类似,卡马西平增加神经管缺陷的风险;然而,它不会增加其他畸形的风险。卡马西平也与发育迟缓风险的增加无关。