腹腔镜骶前神经切除术治疗子宫内膜异位症相关性疼痛的有效性和安全性
[Effectiveness and safety of laparoscopic presacral neurectomy in treating endometriosis-associated pain].
作者信息
Liu Kai-Jiang, Cui Li-Qing, Huang Qian, Liu Qing, Han Na-Na, Li Pei-Quan, Wang Juan
机构信息
Gynecologic Oncology Treatment Center, Affiliated Tumor Hospital of Xinjiang Medical University, Urumqi 830011, China.
出版信息
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2011 Oct;33(5):485-8.
OBJECTIVE
To explore the effectiveness and safety of laparoscopic presacral neurectomy (LPN) in treating endometriosis-associated pain.
METHODS
Totally 64 patients with endometriosis were divided into two groups using prospective non-random method. Patients in the control group received only the conventional laparoscopic resection of endometriosis lesions, while patients in the LPN group underwent LPN in addition to the resection of endometriosis lesions. The pre-operative pain scores, intra-operative staging results, surgical duration, intra-surgical blood loss, post-operative pain relief were compared between these two groups.
RESULTS
These two groups showed no significant differences in terms of age, body weight, pre-operative pain score, surgery staging, surgical duration, and intra-operative blood loss (all P > 0.05). All patients were followed up for 6 to 18 months (median: 12.8 months). The post-operative pain relief rate was 89.28% (25/ 28) in LPN group and 61.29% (19/31) in the control group (P = 0.030).
CONCLUSION
LPN can effectively and safely in treating endometriosis and its associated pain.
目的
探讨腹腔镜骶前神经切除术（LPN）治疗子宫内膜异位症相关疼痛的有效性和安全性。
方法
采用前瞻性非随机方法将64例子宫内膜异位症患者分为两组。对照组患者仅接受传统的腹腔镜下子宫内膜异位症病灶切除术，而LPN组患者除切除子宫内膜异位症病灶外还接受LPN。比较两组患者术前疼痛评分、术中分期结果、手术时间、术中出血量、术后疼痛缓解情况。
结果
两组患者在年龄、体重、术前疼痛评分、手术分期、手术时间和术中出血量方面均无显著差异（均P>0.05）。所有患者均随访6至18个月（中位数：12.8个月）。LPN组术后疼痛缓解率为89.28%（25/28），对照组为61.29%（19/31）（P=0.030）。
结论
LPN能有效、安全地治疗子宫内膜异位症及其相关疼痛。
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